Regulation of Liver Enriched Transcription Factors in Rat Hepatocytes Cultures on Collagen and EHS Sarcoma Matrices

Systems toxicology

(2014) Thomas HArtung   ALTEX-Alternatives to Animal Experimentation

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Long-Term Stability of Primary Rat Hepatocytes in Micropatterned Cocultures

(2013) Okechukwu Ukairo et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Organotypic liver culture models: Meeting current challenges in toxicity testing

(2012) Edward L. LeCluyse et al.   CRITICAL REVIEWS IN TOXICOLOGY

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

(2012) K.-V. Nguyen-Ngoc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro models for liver toxicity testing

(2012) Valerie Y. Soldatow et al.   Toxicology Research

Spherical cell shape of FLC-4 cell, a human hepatoma cell, enhances hepatocyte-specific function and suppresses tumor phenotype through the integration of mRNA–microRNA interaction

(2012) Thomas Laurent et al.   Biology Open

The stable repression of mesenchymal program is required for hepatocyte identity: A novel role for hepatocyte nuclear factor 4α

(2011) Laura Santangelo et al.   HEPATOLOGY

HNF4alpha Dysfunction as a Molecular Rational for Cyclosporine Induced Hypertension

(2011) Monika Niehof et al.   PLoS One

A High Resolution Genome-Wide Scan of HNF4α Recognition Sites Infers a Regulatory Gene Network in Colon Cancer

(2011) Fridtjof Weltmeier et al.   PLoS One

Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research

(2010) Jeanette Bierwolf et al.   BIOTECHNOLOGY AND BIOENGINEERING

Sandwich-cultured hepatocytes: anin vitromodel to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity

(2010) Brandon Swift* et al.   DRUG METABOLISM REVIEWS

Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells

(2010) Gabriel Benton et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of HNF4alpha in the human and rat choroid plexus – Implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrier

(2009) Monika Niehof et al.   BMC MOLECULAR BIOLOGY

Liver-enriched transcription factors are critical for the expression of hepatocyte marker genes in mES-derived hepatocyte-lineage cells

(2009) Pakpoom Kheolamai et al.   BMC MOLECULAR BIOLOGY

Comparative Analysis of Gene Expression in Rat Liver Tissue and Monolayer- and Spheroid-Cultured Hepatocytes

(2009) Yusuke Sakai et al.   CELLS TISSUES ORGANS

HNF4  and the Ca-Channel TRPC1 Are Novel Disease Candidate Genes in Diabetic Nephropathy

(2008) M. Niehof et al.   DIABETES

EPS15R, TASP1, and PRPF3 Are Novel Disease Candidate Genes Targeted by HNF4α Splice Variants in Hepatocellular Carcinomas

(2008) Monika Niehof et al.   GASTROENTEROLOGY

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS

Matrix layer sample preparation: An improved MALDI-MS peptide analysis method for proteomic studies

(2008) Ignazio Garaguso et al.   PROTEOMICS

Three-Dimensional Primary Hepatocyte Culture in Synthetic Self-Assembling Peptide Hydrogel

(2008) Sihong Wang et al.   TISSUE ENGINEERING PART A

Genome wide prediction of HNF4α functional binding sites by the use of local and global sequence context

(2008) Alexander E Kel et al.   GENOME BIOLOGY