A Conserved Transcriptional Signature of Delayed Aging and Reduced Disease Vulnerability Is Partially Mediated by SIRT3

Identification of serum sirtuins as novel noninvasive protein markers for frailty

(2014) Rahul Kumar et al.   AGING CELL

Crosstalk between circadian rhythmicity, mitochondrial dynamics and macrophage bactericidal activity

(2014) Jacqueline Oliva-Ramírez et al.   IMMUNOLOGY

High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice

(2013) Johanna L. Barclay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice

(2013) Yimin Fang et al.   Cell Metabolism

Somatotropic Signaling: Trade-Offs Between Growth, Reproductive Development, and Longevity

(2013) Andrzej Bartke et al.   PHYSIOLOGICAL REVIEWS

Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

(2013) C. B. Peek et al.   SCIENCE

SIRT3 Reverses Aging-Associated Degeneration

(2013) Katharine Brown et al.   Cell Reports

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

(2012) Anna-Maria Joseph et al.   AGING CELL

Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance

(2012) Lovisa E Johansson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The caloric restriction paradigm: Implications for healthy human aging

(2012) Rozalyn M. Anderson et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

Grape Resveratrol Increases Serum Adiponectin and Downregulates Inflammatory Genes in Peripheral Blood Mononuclear Cells: A Triple-Blind, Placebo-Controlled, One-Year Clinical Trial in Patients with Stable Coronary Artery Disease

(2012) João Tomé-Carneiro et al.   CARDIOVASCULAR DRUGS AND THERAPY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity

(2012) E. Arner et al.   DIABETES

A meta-analysis of caloric restriction gene expression profiles to infer common signatures and regulatory mechanisms

(2012) Michael Plank et al.   Molecular BioSystems

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

(2012) Ruben Nogueiras et al.   PHYSIOLOGICAL REVIEWS

Metabolic characteristics of long-lived mice

(2012) Andrzej Bartke et al.   Frontiers in Genetics

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

(2011) Silvie Timmers et al.   Cell Metabolism

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

(2011) Matthew D. Hirschey et al.   MOLECULAR CELL

Mitochondrial sirtuins

(2010) Jing-Yi Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

An 8-Week High-Fat Diet Induces Obesity and Insulin Resistance with Small Changes in the Muscle Transcriptome of C57BL/6J Mice

(2010) Janneke de Wilde et al.   Journal of Nutrigenetics and Nutrigenomics

Powerful signals for weak muscles

(2009) Amarjit Saini et al.   AGEING RESEARCH REVIEWS

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

(2009) Evan T. Powers et al.   Annual Review of Biochemistry

Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

(2009) William R Swindell   BMC GENOMICS

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization

(2009) D. D. Sears et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Metabolic reprogramming, caloric restriction and aging

(2009) Rozalyn M. Anderson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?

(2008) Leonard Guarente   CELL

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism

Role of the GH/IGF-1 axis in lifespan and healthspan: Lessons from animal models

(2008) Darlene E. Berryman et al.   GROWTH HORMONE & IGF RESEARCH

Pioglitazone Enhances Mitochondrial Biogenesis and Ribosomal Protein Biosynthesis in Skeletal Muscle in Polycystic Ovary Syndrome

(2008) Vibe Skov et al.   PLoS One

Comparative analysis of microarray data identifies common responses to caloric restriction among mouse tissues

(2007) William R. Swindell   MECHANISMS OF AGEING AND DEVELOPMENT