Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

(2016) Orsolya M. Palacios et al.   Aging-US

Diabetes mellitus, a complex and heterogeneous disease, and the role of insulin resistance as a determinant of diabetic kidney disease

(2014) Janaka Karalliedde et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Regulation of Skeletal Muscle Oxidative Capacity and Muscle Mass by SIRT3

(2014) Ligen Lin et al.   PLoS One

The impact of age-related dysregulation of the angiotensin system on mitochondrial redox balance

(2014) Ramya Vajapey et al.   Frontiers in Physiology

The role of mitochondria in the aetiology of insulin resistance and type 2 diabetes

(2013) Sheree D. Martin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle

(2013) Josef Brandauer et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Novel Angiotensin II Receptor Blocker Azilsartan Medoxomil Ameliorates Insulin Resistance Induced by Chronic Angiotensin II Treatment in Rat Skeletal Muscle

(2013) Guido Lastra et al.   CardioRenal Medicine

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

The Renin Angiotensin Aldosterone System and Insulin Resistance in Humans

(2012) Patricia C. Underwood et al.   CURRENT HYPERTENSION REPORTS

Propionyl-L-carnitine Corrects Metabolic and Cardiovascular Alterations in Diet-Induced Obese Mice and Improves Liver Respiratory Chain Activity

(2012) Carmen Mingorance et al.   PLoS One

Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine

(2012) Santica M. Marcovina et al.   Translational Research

Mitochondrial oxidative stress and the metabolic syndrome

(2012) Andrew M. James et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

ROS-induced ROS release in vascular biology: redox-redox signaling

(2011) Natalya S. Zinkevich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

The Metabolic Syndrome—from Insulin Resistance to Obesity and Diabetes

(2011) Emily Jane Gallagher et al.   MEDICAL CLINICS OF NORTH AMERICA

The SirT3 Divining Rod Points to Oxidative Stress

(2011) Eric L. Bell et al.   MOLECULAR CELL

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct inhibition by angiotensin II of insulin-dependent glucose transport activity in mammalian skeletal muscle involves a ROS-dependent mechanism

(2010) Maggie K. Diamond-Stanic et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Mitochondria in the elderly: Is acetylcarnitine a rejuvenator?☆

(2009) Mariana G. Rosca et al.   ADVANCED DRUG DELIVERY REVIEWS

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

(2009) Christian Pehmøller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skeletal muscle NAMPT is induced by exercise in humans

(2009) Sheila R. Costford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Vitagenes, cellular stress response, and acetylcarnitine: Relevance to hormesis

(2009) Vittorio Calabrese et al.   BIOFACTORS

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

Nicotinamide Phosphoribosyltransferase (Nampt): A Link Between NAD Biology, Metabolism, and Diseases

(2009) Shin-ichiro Imai   CURRENT PHARMACEUTICAL DESIGN

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

(2009) R. A. DeFronzo et al.   DIABETES CARE

Acetyl-l-carnitine inhibits TNF-α-induced insulin resistance via AMPK pathway in rat skeletal muscle cells

(2009) Zhaofeng Zhang et al.   FEBS LETTERS

Ameliorating Hypertension and Insulin Resistance in Subjects at Increased Cardiovascular Risk

(2009) Piero Ruggenenti et al.   HYPERTENSION

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of the Ang II type 1 receptor promotes longevity in mice

(2009) Ariela Benigni et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Syndrome Pandemic

(2008) Scott M. Grundy   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism

(2008) C. A. Witczak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of Mitochondrial Dysfunction in Insulin Resistance

(2008) Jeong-a Kim et al.   CIRCULATION RESEARCH

Angiotensin II Reduces Mitochondrial Content in Skeletal Muscle and Affects Glycemic Control

(2008) M. Mitsuishi et al.   DIABETES

Angiotensin II and the development of insulin resistance: Implications for diabetes

(2008) J. Alberto Olivares-Reyes et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-κB activation via NADPH oxidase

(2007) Yongzhong Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM