Repurposing Salicylanilide Anthelmintic Drugs to Combat Drug Resistant Staphylococcus aureus

ACaenorhabditis elegansHost Model Correlates with Invasive Disease Caused byStaphylococcus aureusRecovered during an Outbreak in Neonatal Intensive Care

(2016) Kaiyu Wu et al.   Canadian Journal of Infectious Diseases & Medical Microbiology

Insect-Derived Cecropins Display Activity against Acinetobacter baumannii in a Whole-Animal High-Throughput Caenorhabditis elegans Model

(2015) Elamparithi Jayamani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and in vitro biological evaluation of 2-(phenylcarbamoyl)phenyl 4-substituted benzoates

(2015) Martin Krátký et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis

(2014) Bumsup Kwon et al.   HUMAN MOLECULAR GENETICS

Niclosamide ethanolamine–induced mild mitochondrial uncoupling improves diabetic symptoms in mice

(2014) Hanlin Tao et al.   NATURE MEDICINE

Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus

(2014) Rajmohan Rajamuthiah et al.   PLoS One

The Anthelmintic Drug Niclosamide Induces Apoptosis, Impairs Metastasis and Reduces Immunosuppressive Cells in Breast Cancer Model

(2014) Tinghong Ye et al.   PLoS One

Antibacterial Activity of THAM Trisphenylguanide against Methicillin-Resistant Staphylococcus aureus

(2014) Alan J. Weaver et al.   PLoS One

Overcoming the current deadlock in antibiotic research

(2014) Till F. Schäberle et al.   TRENDS IN MICROBIOLOGY

Effector triggered immunity

(2014) Rajmohan Rajamuthiah et al.   Virulence

New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species

(2013) Karel Pauk et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death

(2013) Natalia V. Kirienko et al.   Cell Host & Microbe

Antibacterial Activity of Salicylanilide 4-(Trifluoromethyl)-benzoates

(2013) Martin Krátký et al.   MOLECULES

Toward Repurposing Ciclopirox as an Antibiotic against Drug-Resistant Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae

(2013) Kimberly M. Carlson-Banning et al.   PLoS One

An Extensive Comparison of the Effect of Anthelmintic Classes on Diverse Nematodes

(2013) Yan Hu et al.   PLoS One

Niclosamide suppresses hepatoma cell proliferation via the Wnt pathway

(2013) Minoru Tomizawa et al.   OncoTargets and Therapy

Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting

(2012) Jun-Jie Koh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Community-associated and healthcare-associated methicillin-resistantStaphylococcus aureusvirulence towardCaenorhabditis eleganscompared

(2012) Shandra R. Day et al.   Virulence

Pharmacological Properties of the Marine Natural Product Marinopyrrole A against Methicillin-Resistant Staphylococcus aureus

(2011) Nina M. Haste et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

(2011) Lee Kamentsky et al.   BIOINFORMATICS

Challenges of Antibacterial Discovery

(2011) L. L. Silver   CLINICAL MICROBIOLOGY REVIEWS

C. elegans: model host and tool for antimicrobial drug discovery

(2011) J. J. Ewbank et al.   Disease Models & Mechanisms

UsingCaenorhabditis elegansfor antimicrobial drug discovery

(2011) Athanasios Desalermos et al.   Expert Opinion on Drug Discovery

Whole-Genome Sequencing of Staphylococcus aureus Strain RN4220, a Key Laboratory Strain Used in Virulence Research, Identifies Mutations That Affect Not Only Virulence Factors but Also the Fitness of the Strain

(2011) D. Nair et al.   JOURNAL OF BACTERIOLOGY

Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

(2011) Wenyan Lu et al.   PLoS One

High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase

(2010) Ting-Jen Rachel Cheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Progress and Challenges in Implementing the Research on ESKAPE Pathogens

(2010) Louis B. Rice   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Repurposing FDA-approved drugs to combat drug-resistant Acinetobacter baumannii

(2010) S. Chopra et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease

(2010) Jason W. Rosch et al.   JOURNAL OF CLINICAL INVESTIGATION

Synthesis and antiproliferative activities against Hep-G2 of salicylanide derivatives: potent inhibitors of the epidermal growth factor receptor (EGFR) tyrosine kinase

(2010) Zhen-Wei Zhu et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Distinct Pathogenesis and Host Responses during Infection of C. elegans by P. aeruginosa and S. aureus

(2010) Javier E. Irazoqui et al.   PLoS Pathogens

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model

(2009) Terence I. Moy et al.   ACS Chemical Biology

Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices

(2009) James H. Jorgensen et al.   CLINICAL INFECTIOUS DISEASES

Epidemiology of Methicillin‐ResistantStaphylococcus aureus

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES