Oxidative DNA Damage in Kidneys and Heart of Hypertensive Mice Is Prevented by Blocking Angiotensin II and Aldosterone Receptors

8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: The SABPA study

(2014) C. M.C. Mels et al.   FREE RADICAL RESEARCH

Diurnal variation of urinary markers of nucleic acid oxidation

(2014) Ida S. Grew et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid

(2013) Henrik E. Poulsen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

AntioxidantN-Acetylcysteine Protects Pancreatic β-Cells Against Aldosterone-Induced Oxidative Stress and Apoptosis in Femaledb/dbMice and Insulin-Producing MIN6 Cells

(2013) Hui Min Jin et al.   ENDOCRINOLOGY

Eplerenone-Mediated Aldosterone Blockade Prevents Renal Fibrosis by Reducing Renal Inflammation, Interstitial Cell Proliferation and Oxidative Stress

(2013) Hui Chen et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease

(2013) Amy McCurley et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

A new and fast methodology to assess oxidative damage in cardiovascular diseases risk development through eVol-MEPS–UHPLC analysis of four urinary biomarkers

(2013) Berta Mendes et al.   TALANTA

Oxidative stress in vascular disease and its pharmacological prevention

(2013) Huige Li et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System

(2012) Bernard Lassègue et al.   CIRCULATION RESEARCH

Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats

(2012) Sunil K. Panchal et al.   EUROPEAN JOURNAL OF NUTRITION

Role of Nox4 in murine models of kidney disease

(2012) Andrea Babelova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Blood pressure has only minor influence on aldosterone-induced oxidative stress and DNA damage in vivo

(2012) Nina Queisser et al.   FREE RADICAL BIOLOGY AND MEDICINE

Angiotensin II-induced hypertension dose-dependently leads to oxidative stress and DNA damage in mouse kidneys and hearts

(2012) Susanne Brand et al.   JOURNAL OF HYPERTENSION

Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4

(2012) G. Fazeli et al.   MUTAGENESIS

Suppression of Nrf2 signaling by angiotensin II in murine renal epithelial cells

(2011) Su Jin Kang et al.   ARCHIVES OF PHARMACAL RESEARCH

NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies

(2011) Alexander Sirker et al.   BASIC RESEARCH IN CARDIOLOGY

The Epidemiology of Renal Cell Carcinoma

(2011) Börje Ljungberg et al.   EUROPEAN UROLOGY

Age-related changes in renal expression of oxidant and antioxidant enzymes and oxidative stress markers in male SHR and WKY rats

(2011) Sónia Simão et al.   EXPERIMENTAL GERONTOLOGY

Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension

(2011) Manuel Gómez-Guzmán et al.   FREE RADICAL BIOLOGY AND MEDICINE

IκBβ Attenuates Angiotensin II–Induced Cardiovascular Inflammation and Fibrosis in Mice

(2011) Shanqin Xu et al.   HYPERTENSION

Role of Intrarenal Angiotensin System Activation, Oxidative Stress, Inflammation, and Impaired Nuclear Factor-Erythroid-2-Related Factor 2 Activity in the Progression of Focal Glomerulosclerosis

(2011) H. J. Kim et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR

(2011) Ana M. Briones et al.   Journal of the American Society of Hypertension

Variants in blood pressure genes and the risk of renal cell carcinoma

(2010) Gabriella Andreotti et al.   CARCINOGENESIS

Aldosterone-induced kidney injury is mediated by NFκB activation

(2010) Seiichi Fukuda et al.   Clinical and Experimental Nephrology

Aldosterone Causes DNA Strand Breaks and Chromosomal Damage in Renal Cells, Which are Prevented by Mineralocorticoid Receptor Antagonists

(2010) N. Schupp et al.   HORMONE AND METABOLIC RESEARCH

Elevated Mineralocorticoid Receptor Activity in Aged Rat Vascular Smooth Muscle Cells Promotes a Proinflammatory Phenotype via Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase and Epidermal Growth Factor Receptor-Dependent Pathways

(2010) Alexander W. Krug et al.   HYPERTENSION

Endothelial Nitric Oxide Synthase–Independent Protective Action of Statin Against Angiotensin II–Induced Atrial Remodeling via Reduced Oxidant Injury

(2010) Shusuke Yagi et al.   HYPERTENSION

Metabolic syndrome and risk of bladder cancer: prospective cohort study in the metabolic syndrome and cancer project (Me-Can)

(2010) Christel Häggström et al.   INTERNATIONAL JOURNAL OF CANCER

Aldosterone induces oxidative stress, oxidative DNA damage and NF-κB-activation in kidney tubule cells

(2010) Nina Queisser et al.   MOLECULAR CARCINOGENESIS

Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats

(2010) H. Kawarazaki et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Blood pressure and risk of prostate cancer: cohort Norway (CONOR)

(2009) Richard M. Martin et al.   CANCER CAUSES & CONTROL

A Longitudinal Study of the Metabolic Syndrome and Risk of Postmenopausal Breast Cancer

(2009) G. C. Kabat et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

ROLE OF ACTIVATED INTRARENAL REACTIVE OXYGEN SPECIES AND RENIN-ANGIOTENSIN SYSTEM IN IgA NEPHROPATHY MODEL MICE

(2009) Naro Ohashi et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt

(2009) William B. Lea et al.   KIDNEY INTERNATIONAL

Antioxidant SOD Mimetic Prevents NADPH Oxidase-Induced Oxidative Stress and Renal Damage in the Early Stage of Experimental Diabetes and Hypertension

(2008) Elisa B.M.I. Peixoto et al.   AMERICAN JOURNAL OF NEPHROLOGY

Angiotensin II Induces DNA Damage in the Kidney

(2008) U. Schmid et al.   CANCER RESEARCH

Spironolactone exhibits direct renoprotective effects and inhibits renal renin–angiotensin–aldosterone system in diabetic rats

(2008) Masateru Taira et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Inflammation in the Development of Renal Damage and Dysfunction in Angiotensin II–Induced Hypertension

(2008) Tang-Dong Liao et al.   HYPERTENSION

Hypertension Induces Somatic Cellular Senescence in Rats and Humans by Induction of Cell Cycle Inhibitor p16 INK4a

(2008) Jens H. Westhoff et al.   HYPERTENSION

Spironolactone suppresses inflammation and prevents L-NAME–induced renal injury in rats

(2008) Hirofumi Ikeda et al.   KIDNEY INTERNATIONAL

Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension

(2008) B. Klanke et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Glucosyl hesperidin prevents endothelial dysfunction and oxidative stress in spontaneously hypertensive rats

(2008) Masaki Yamamoto et al.   NUTRITION

Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides

(2008) C. S. Wilcox et al.   PHARMACOLOGICAL REVIEWS

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

Blood Pressure and Risk of Renal Cell Carcinoma in the European Prospective Investigation into Cancer and Nutrition

(2007) S. Weikert et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY