Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

(2014) Lucie Kosinová et al.   BIOCHEMISTRY

Protective hinge in insulin opens to enable its receptor engagement

(2014) J. G. Menting et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality

(2013) Lenka Žáková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How insulin engages its primary binding site on the insulin receptor

(2013) John G. Menting et al.   NATURE

Maturity onset diabetes of the young: identification and diagnosis

(2013) T. J. McDonald et al.   ANNALS OF CLINICAL BIOCHEMISTRY

CING: an integrated residue-based structure validation program suite

(2012) Jurgen F. Doreleijers et al.   JOURNAL OF BIOMOLECULAR NMR

Design of the Novel Protraction Mechanism of Insulin Degludec, an Ultra-long-Acting Basal Insulin

(2012) Ib Jonassen et al.   PHARMACEUTICAL RESEARCH

Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface

(2011) Emília Antolíková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Review on monogenic diabetes

(2011) Andrea K. Steck et al.   Current Opinion in Endocrinology Diabetes and Obesity

Insulin gene mutations and diabetes

(2011) Masahiro Nishi et al.   Journal of Diabetes Investigation

Mutant INS-Gene Induced Diabetes of Youth: Proinsulin Cysteine Residues Impose Dominant-Negative Inhibition on Wild-Type Proinsulin Transport

(2010) Ming Liu et al.   PLoS One

Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues

(2010) J. Jiracek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inactive conformation of an insulin despite its wild-type sequence

(2010) Gunther Kurapkat et al.   PROTEIN SCIENCE

Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene

(2010) Julie Støy et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

(2009) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Insulin Analogues with Modifications at Position B26. Divergence of Binding Affinity and Biological Activity†

(2008) Lenka Žáková et al.   BIOCHEMISTRY

Mutations in the Insulin Gene Can Cause MODY and Autoantibody-Negative Type 1 Diabetes

(2008) A. Molven et al.   DIABETES