Proteasome Inhibitors Activate Autophagy Involving Inhibition of PI3K-Akt-mTOR Pathway as an Anti-Oxidation Defense in Human RPE Cells
出版年份 2014 全文链接
标题
Proteasome Inhibitors Activate Autophagy Involving Inhibition of PI3K-Akt-mTOR Pathway as an Anti-Oxidation Defense in Human RPE Cells
作者
关键词
Autophagic cell death, Proteasomes, MTS assay, Lysosomes, Proteasome inhibitors, Small interfering RNAs, Toxicity, Cell viability testing
出版物
PLoS One
Volume 9, Issue 7, Pages e103364
出版商
Public Library of Science (PLoS)
发表日期
2014-07-26
DOI
10.1371/journal.pone.0103364
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy
- (2014) You-Tong Wu et al. Autophagy
- Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization
- (2014) Jingjing Cai et al. Journal of Neuroinflammation
- A novel crosstalk between two major protein degradation systems
- (2013) Xiao J Wang et al. Autophagy
- Rapalogs and mTOR inhibitors as anti-aging therapeutics
- (2013) Dudley W. Lamming et al. JOURNAL OF CLINICAL INVESTIGATION
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- ULK1, Mammalian Target of Rapamycin, and Mitochondria: Linking Nutrient Availability and Autophagy
- (2011) Mondira Kundu ANTIOXIDANTS & REDOX SIGNALING
- Rosiglitazone induces autophagy in H295R and cell cycle deregulation in SW13 adrenocortical cancer cells
- (2011) Lidia Cerquetti et al. EXPERIMENTAL CELL RESEARCH
- EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells
- (2011) Weidong Han et al. PLoS One
- Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death
- (2010) Donelly A. van Schalkwyk et al. BIOCHEMICAL PHARMACOLOGY
- Resveratrol Promotes Autophagic Cell Death in Chronic Myelogenous Leukemia Cells via JNK-Mediated p62/SQSTM1 Expression and AMPK Activation
- (2010) A. Puissant et al. CANCER RESEARCH
- A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease
- (2009) Ken Cadwell et al. Autophagy
- In search of an “autophagomometer”
- (2009) David C. Rubinsztein et al. Autophagy
- Cellular calcium deficiency plays a role in neuronal death caused by proteasome inhibitors
- (2009) Shengzhou Wu et al. JOURNAL OF NEUROCHEMISTRY
- Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
- (2009) Viktor I. Korolchuk et al. MOLECULAR CELL
- Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells
- (2009) K Zhu et al. ONCOGENE
- Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells
- (2008) William Ka Kei Wu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started