Estrogen regulates T helper 17 phenotype and localization in experimental autoimmune arthritis

OP0193 The Rheumatoid Arthritis -Risk Locus CCR6 and Its Snp-Dependent Response to Estrogen: A Possible Genomic Link between Sex Hormones and the IL-17 Inflammatory Pathway

(2014) M.-F. Ho et al.   ANNALS OF THE RHEUMATIC DISEASES

The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on arthritis

(2014) Cecilia Engdahl et al.   ARTHRITIS RESEARCH & THERAPY

Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study

(2012) Mark C Genovese et al.   ANNALS OF THE RHEUMATIC DISEASES

Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs

(2012) Jason G. Cyster et al.   Annual Review of Immunology

IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner

(2012) Carl J. DeSelm et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Estrogen Deficiency Induces the Differentiation of IL-17 Secreting Th17 Cells: A New Candidate in the Pathogenesis of Osteoporosis

(2012) Abdul M. Tyagi et al.   PLoS One

Sphingosine-1-phospate receptor 4 (S1P4) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model

(2011) Tobias Schulze et al.   FASEB JOURNAL

Estrogen Receptor   Signaling in T Lymphocytes Is Required for Estradiol-Mediated Inhibition of Th1 and Th17 Cell Differentiation and Protection against Experimental Autoimmune Encephalomyelitis

(2011) K. Lelu et al.   JOURNAL OF IMMUNOLOGY

Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis

(2011) Ulrika Islander et al.   ARTHRITIS RESEARCH & THERAPY

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Role of Th17 cells in human autoimmune arthritis

(2010) Jan Leipe et al.   ARTHRITIS AND RHEUMATISM

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

Evidence for a cross-talk between human neutrophils and Th17 cells

(2009) M. Pelletier et al.   BLOOD

Disease modifying and antiangiogenic activity of 2-Methoxyestradiol in a murine model of rheumatoid arthritis

(2009) Stacy M Plum et al.   BMC MUSCULOSKELETAL DISORDERS

Regulation of dendritic cell differentiation and function by estrogen receptor ligands

(2008) Susan Kovats et al.   CELLULAR IMMUNOLOGY

Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin-17 production via programmed death 1

(2008) Chunhe Wang et al.   IMMUNOLOGY

Evidence for PI-3K-dependent migration of Th17-polarized cells in response to CCR2 and CCR6 agonists

(2008) Adam Webb et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Orchestrating the orchestrators: chemokines in control of T cell traffic

(2008) Shannon K Bromley et al.   NATURE IMMUNOLOGY