Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

Interactions of T Cells with Fibroblast-Like Synoviocytes: Role of the B7 Family Costimulatory Ligand B7-H3

(2014) C. N. Tran et al.   JOURNAL OF IMMUNOLOGY

Regulation of IL-17 in Human CCR6+ Effector Memory T Cells

(2014) H. Liu et al.   JOURNAL OF IMMUNOLOGY

Th17 cytokines and arthritis

(2010) Erik Lubberts   Seminars in Immunopathology

GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis

(2009) Jan Piet van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

(2009) Hui Shen et al.   ARTHRITIS AND RHEUMATISM

Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis

(2009) Alexei von Delwig et al.   ARTHRITIS AND RHEUMATISM

1,25-dihydroxyvitamin D3modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis

(2009) E. M. Colin et al.   ARTHRITIS AND RHEUMATISM

Differentiation and functional analysis of human TH17 cells

(2009) Simone Burgler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

(2009) Peter C. Taylor et al.   Nature Reviews Rheumatology

Type 17 T helper cells—origins, features and possible roles in rheumatic disease

(2009) Francesco Annunziato et al.   Nature Reviews Rheumatology

Garden of therapeutic delights: new targets in rheumatic diseases

(2009) Jean M Waldburger et al.   ARTHRITIS RESEARCH & THERAPY

Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers

(2008) Kiran Nistala et al.   ARTHRITIS AND RHEUMATISM

Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion

(2008) C. Chizzolini et al.   BLOOD

Th17 Cell Differentiation: The Long and Winding Road

(2008) Mandy J. McGeachy et al.   IMMUNITY

Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction

(2008) Hideki Ogura et al.   IMMUNITY

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

(2008) Clare A. Notley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair?

(2008) Gillian Murphy et al.   Nature clinical practice. Rheumatology

IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?

(2007) Erik Lubberts   CYTOKINE