Comparison of the Anti-Prion Mechanism of Four Different Anti-Prion Compounds, Anti-PrP Monoclonal Antibody 44B1, Pentosan Polysulfate, Chlorpromazine, and U18666A, in Prion-Infected Mouse Neuroblastoma Cells

Live imaging of prions reveals nascent PrPScin cell-surface, raft-associated amyloid strings and webs

(2014) Alexander Rouvinski et al.   JOURNAL OF CELL BIOLOGY

Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrPSc during early stage prion infection in Neuro2a cells

(2014) Takeshi Yamasaki et al.   VIROLOGY

FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice

(2013) Takehiro Nakagaki et al.   Autophagy

Therapy in Prion Diseases

(2013) Gianluigi Forloni et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

4-hydroxytamoxifen leads to PrPSc clearance by conveying both PrPC and PrPSc to lysosomes independently of autophagy

(2013) L. Marzo et al.   JOURNAL OF CELL SCIENCE

Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease

(2013) M. D. Geschwind et al.   NEUROLOGY

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

Characterization of intracellular localization of PrPSc in prion-infected cells using a mAb that recognizes the region consisting of aa 119-127 of mouse PrP

(2011) T. Yamasaki et al.   JOURNAL OF GENERAL VIROLOGY

Stem Cell Therapy Extends Incubation and Survival Time in Prion-Infected Mice in a Time Window–Dependant Manner

(2011) Aroa Relaño-Ginés et al.   JOURNAL OF INFECTIOUS DISEASES

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Autophagy induction by trehalose counter-acts cellular prion-infection

(2009) Yasmine Aguib et al.   Autophagy

Inhibition of cholesterol recycling impairs cellular PrPSc propagation

(2009) Sabine Gilch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cell density-dependent increase in the level of protease-resistant prion protein in prion-infected Neuro2a mouse neuroblastoma cells

(2009) S. Nakamitsu et al.   JOURNAL OF GENERAL VIROLOGY

Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy

(2009) Andreas Heiseke et al.   JOURNAL OF NEUROCHEMISTRY

Effect of Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells on Mice Infected with Prions

(2009) C.-H. Song et al.   JOURNAL OF VIROLOGY

Continuous intraventricular infusion of pentosan polysulfate: Clinical trial against prion diseases

(2009) Yoshio Tsuboi et al.   NEUROPATHOLOGY

Prions: Protein Aggregation and Infectious Diseases

(2009) Adriano Aguzzi et al.   PHYSIOLOGICAL REVIEWS

Identification of an Intracellular Site of Prion Conversion

(2009) Zrinka Marijanovic et al.   PLoS Pathogens

Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy

(2008) Nathalie M. Veith et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Intraventricular pentosan polysulphate in human prion diseases: an observational study in the UK

(2008) I. Bone et al.   EUROPEAN JOURNAL OF NEUROLOGY

Cellular cholesterol trafficking and compartmentalization

(2008) Elina Ikonen   NATURE REVIEWS MOLECULAR CELL BIOLOGY