Exendin-4 Reduces Ischemic Brain Injury in Normal and Aged Type 2 Diabetic Mice and Promotes Microglial M2 Polarization

Acute Ischemic Stroke

(2014) Nathan W. Manning et al.   STROKE

Toll-Like Receptor-3 Activation Increases the Vulnerability of the Neonatal Brain to Hypoxia-Ischemia

(2013) L. Stridh et al.   JOURNAL OF NEUROSCIENCE

The science of cerebral ischemia and the quest for neuroprotection: navigating past failure to future success

(2013) Ryan C. Turner et al.   JOURNAL OF NEUROSURGERY

Age-related changes in brain support cells: Implications for stroke severity

(2013) Farida Sohrabji et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective and neurotrophic actions of glucagon-like peptide-1: an emerging opportunity to treat neurodegenerative and cerebrovascular disorders

(2012) Isidro Salcedo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel therapeutic strategies targeting innate immune responses and early inflammation after stroke

(2012) Takashi Shichita et al.   JOURNAL OF NEUROCHEMISTRY

Reducing in-hospital delay to 20 minutes in stroke thrombolysis

(2012) A. Meretoja et al.   NEUROLOGY

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Repeated administration of exendin-4 reduces focal cerebral ischemia-induced infarction in rats

(2011) Seema Briyal et al.   BRAIN RESEARCH

Glucagon-like peptide-1 receptor activation reduces ischaemic brain damage following stroke in Type 2 diabetic rats

(2011) Vladimer Darsalia et al.   CLINICAL SCIENCE

Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia

(2011) Choong Hyun Lee et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Glucagon-like peptide 1 receptor stimulation as a means of neuroprotection

(2010) Alexander Harkavyi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Reducing the risk of stroke in type 2 diabetes: pathophysiological and therapeutic perspectives

(2009) Dirk Sander et al.   JOURNAL OF NEUROLOGY

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system

(2009) Alison Hamilton et al.   NEUROREPORT

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

(2009) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy and Safety of Tissue Plasminogen Activator 3 to 4.5 Hours After Acute Ischemic Stroke

(2009) Maarten G. Lansberg et al.   STROKE

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

The protective effect of risk factors against stroke severity

(2008) Israel Steiner et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES