Emerging Role of Long Non-Coding RNA SOX2OT in SOX2 Regulation in Breast Cancer

Evidence for the Existence of Triple-Negative Variants in the MCF-7 Breast Cancer Cell Population

(2014) Euphemia Leung et al.   Biomed Research International

Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway

(2013) BRUNA COROMINAS-FAJA et al.   CELL CYCLE

Sox2 promotes tamoxifen resistance in breast cancer cells

(2013) Marco Piva et al.   EMBO Molecular Medicine

In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity

(2013) Chanel E. Smart et al.   PLoS One

Identification of expressed and conserved human noncoding RNAs

(2013) M. M. Nielsen et al.   RNA

Two Novel Splice Variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are Coupregulated with SOX2 and OCT4 in Esophageal Squamous Cell Carcinoma

(2013) Alireza Shahryari et al.   STEM CELLS

The effect of a thieno[2,3-b]pyridine PLC-γ inhibitor on the proliferation, morphology, migration and cell cycle of breast cancer cells

(2013) Euphemia Leung et al.   MedChemComm

Identification of two novel phenotypically distinct breast cancer cell subsets based on Sox2 transcription activity

(2012) Fang Wu et al.   CELLULAR SIGNALLING

Elevating SOX2 Levels Deleteriously Affects the Growth of Medulloblastoma and Glioblastoma Cells

(2012) Jesse L. Cox et al.   PLoS One

The enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugs

(2011) Lei Chen et al.   BIOMATERIALS

Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma

(2011) Claudia Lengerke et al.   BMC CANCER

Comparison of the effects of the PI3K/mTOR inhibitors NVP-BEZ235 and GSK2126458 on tamoxifen-resistant breast cancer cells

(2011) Euphemia Leung et al.   CANCER BIOLOGY & THERAPY

Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: effects on tamoxifen-resistant MCF-7 cancer cells

(2011) Euphemia Leung et al.   INVESTIGATIONAL NEW DRUGS

SOX2 contributes to melanoma cell invasion

(2011) Sasha D Girouard et al.   LABORATORY INVESTIGATION

Distinct Functions of Sox2 Control Self-Renewal and Differentiation in the Osteoblast Lineage

(2011) E. Seo et al.   MOLECULAR AND CELLULAR BIOLOGY

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

(2011) U Basu-Roy et al.   ONCOGENE

Sox2 expression in breast tumours and activation in breast cancer stem cells

(2011) O Leis et al.   ONCOGENE

Genetic and Epigenetic Modifications of Sox2 Contribute to the Invasive Phenotype of Malignant Gliomas

(2011) Marta M. Alonso et al.   PLoS One

SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer

(2011) M. E. Askarian-Amiri et al.   RNA

Effects of estrogen on the proportion of stem cells in the breast

(2010) Bruno M. Simões et al.   BREAST CANCER RESEARCH AND TREATMENT

MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity

(2010) Euphemia Leung et al.   CANCER BIOLOGY & THERAPY

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

(2009) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

(2009) P. P. Amaral et al.   RNA

The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer

(2008) Yupeng Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS