Toll-Like Receptor 4 Mutant and Null Mice Retain Morphine-Induced Tolerance, Hyperalgesia, and Physical Dependence

Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl− homeostasis

(2013) Francesco Ferrini et al.   NATURE NEUROSCIENCE

Microglial activation involved in morphine tolerance is not mediated by toll-like receptor 4

(2012) Hiroshi Fukagawa et al.   Journal of Anesthesia

Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

(2012) M. R. Hutchinson et al.   JOURNAL OF NEUROSCIENCE

Minocycline blocks lipopolysaccharide induced hyperalgesia by suppression of microglia but not astrocytes

(2012) S.-Y. Yoon et al.   NEUROSCIENCE

Morphine activates neuroinflammation in a manner parallel to endotoxin

(2012) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: Comparison of different mouse strains

(2011) Liang Liu et al.   BRAIN BEHAVIOR AND IMMUNITY

Naloxone and Ouabain in Ultralow Concentrations Restore Na+/K+-ATPase and Cytoskeleton in Lipopolysaccharide-treated Astrocytes

(2011) Johan Forshammar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

The Effect of Morphine on Glial Cells as a Potential Therapeutic Target for Pharmacological Development of Analgesic Drugs

(2010) Haroon Hameed et al.   Current Pain and Headache Reports

Ultra-Low Dose Naltrexone Attenuates Chronic Morphine-Induced Gliosis in Rats

(2010) Theresa-Alexandra M Mattioli et al.   Molecular Pain

Inhibition of microglial P2X4 receptors attenuates morphine tolerance, Iba1, GFAP and μ opioid receptor protein expression while enhancing perivascular microglial ED2

(2010) Ryan J. Horvath et al.   PAIN

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

(2009) Mark R. Hutchinson et al.   BRAIN BEHAVIOR AND IMMUNITY

Morphine Enhances Microglial Migration through Modulation of P2X4 Receptor Signaling

(2009) R. J. Horvath et al.   JOURNAL OF NEUROSCIENCE

Glial TLR4 receptor as new target to treat neuropathic pain: Efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice

(2008) Isabella Bettoni et al.   GLIA