JNK Contributes to the Tumorigenic Potential of Human Cholangiocarcinoma Cells through the mTOR Pathway Regulated GRP78 Induction

Oncogenic Activity of Retinoic Acid Receptor γ Is Exhibited through Activation of the Akt/NF-κB and Wnt/β-Catenin Pathways in Cholangiocarcinoma

(2013) Gui-Li Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells

(2013) Catherine A Taylor et al.   Molecular Cancer

Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78

(2013) Cun Wang et al.   PLoS One

Thiazolidinediones Promote Axonal Growth through the Activation of the JNK Pathway

(2013) Rodrigo A. Quintanilla et al.   PLoS One

Cancer Cells Resistant to Therapy Promote Cell Surface Relocalization of GRP78 Which Complexes with PI3K and Enhances PI(3,4,5)P3 Production

(2013) Yi Zhang et al.   PLoS One

JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis

(2013) Yeo-Woon Ki et al.   TOXICOLOGY LETTERS

GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy

(2013) M Firczuk et al.   Cell Death & Disease

Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells

(2013) Y-C Yang et al.   Cell Death & Disease

A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

(2013) A D Kim et al.   Cell Death & Disease

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Disturbance of Ca2+Homeostasis Converts Pro-Met into Non-canonical Tyrosine Kinase p190MetNCin Response to Endoplasmic Reticulum Stress in MHCC97 Cells

(2012) Rongyang Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Tyrosine Kinase c-Met Contributes to the Pro-tumorigenic Function of the p38 Kinase in Human Bile Duct Cholangiocarcinoma Cells

(2012) Rongyang Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osmotic Stress Regulates Mammalian Target of Rapamycin (mTOR) Complex 1 via c-Jun N-terminal Kinase (JNK)-mediated Raptor Protein Phosphorylation

(2012) Dongoh Kwak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of the Eukaryotic Translation Initiation Factor 4E-Transporter (4E-T) by c-Jun N-Terminal Kinase Promotes Stress-Dependent P-Body Assembly

(2012) M. Cargnello et al.   MOLECULAR AND CELLULAR BIOLOGY

Stressor-Like Effects of c-Jun N-Terminal Kinase (JNK) Inhibition

(2012) Melanie Clarke et al.   PLoS One

Receptor-Recognized α2-Macroglobulin Binds to Cell Surface-Associated GRP78 and Activates mTORC1 and mTORC2 Signaling in Prostate Cancer Cells

(2012) Uma K. Misra et al.   PLoS One

Silencing of miR-370 in Human Cholangiocarcinoma by Allelic Loss and Interleukin-6 Induced Maternal to Paternal Epigenotype Switch

(2012) Fangmei An et al.   PLoS One

JNK2 is activated during ER stress and promotes cell survival

(2012) M Raciti et al.   Cell Death & Disease

A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization during Tumor Growth and Metastasis

(2011) D. Dong et al.   CANCER RESEARCH

The AMPK stress response pathway mediates anoikis resistance through inhibition of mTOR and suppression of protein synthesis

(2011) T L Ng et al.   CELL DEATH AND DIFFERENTIATION

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

Grp78 promotes the invasion of hepatocellular carcinoma

(2010) Rongjian Su et al.   BMC CANCER

GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy

(2010) Eunjung Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP

(2010) Yi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lead Induces the Expression of Endoplasmic Reticulum Chaperones GRP78 and GRP94 in Vascular Endothelial Cells via the JNK-AP-1 Pathway

(2010) Yasuhiro Shinkai et al.   TOXICOLOGICAL SCIENCES

Drosophila happyhour modulates JNK-dependent apoptosis

(2010) D Lam et al.   Cell Death & Disease

Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells

(2010) H L Bennett et al.   Cell Death & Disease

Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

(2009) Miao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity

(2009) Rong-Yang Dai et al.   CELL RESEARCH

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70

(2008) Minjing Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE