CDC42 Use in Viral Cell Entry Processes by RNA Viruses

Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathways

(2014) Mark Spear et al.   IMMUNOLOGICAL REVIEWS

Cdc42 inhibitor ML141 enhances G-CSF-induced hematopoietic stem and progenitor cell mobilization

(2014) Chong Chen et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

HIV-1 Triggers WAVE2 Phosphorylation in Primary CD4 T Cells and Macrophages, Mediating Arp2/3-dependent Nuclear Migration

(2014) Mark Spear et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rotaviruses Reach Late Endosomes and Require the Cation-Dependent Mannose-6-Phosphate Receptor and the Activity of Cathepsin Proteases To Enter the Cell

(2014) M. A. Diaz-Salinas et al.   JOURNAL OF VIROLOGY

Actin Dynamics, Architecture, and Mechanics in Cell Motility

(2014) Laurent Blanchoin et al.   PHYSIOLOGICAL REVIEWS

Restrictions to HIV-1 replication in resting CD4+ T lymphocytes

(2013) Xiaoyu Pan et al.   CELL RESEARCH

Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells

(2013) Hsing-Yu Chen et al.   EMBO Molecular Medicine

Targeting Cdc42 in cancer

(2013) Luis E Arias-Romero et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe

(2013) Lin Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses cell motility

(2013) Amy Friesland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Cell Entry of Respiratory Syncytial Virus Involves Macropinocytosis Followed by Proteolytic Activation of the F Protein

(2013) Magdalena Anna Krzyzaniak et al.   PLoS Pathogens

The Spike Protein VP4 Defines the Endocytic Pathway Used by Rotavirus To Enter MA104 Cells

(2012) Marco A. Díaz-Salinas et al.   JOURNAL OF VIROLOGY

SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

(2012) Hanna-Mari Baldauf et al.   NATURE MEDICINE

The trinity of the cortical actin in the initiation of HIV-1 infection

(2012) Mark Spear et al.   Retrovirology

Rho GTPases and their roles in cancer metabolism

(2012) Kristin F. Wilson et al.   TRENDS IN MOLECULAR MEDICINE

LIM Kinase 1 Modulates Cortical Actin and CXCR4 Cycling and Is Activated by HIV-1 to Initiate Viral Infection

(2011) Paul J. Vorster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ebola Virus Enters Host Cells by Macropinocytosis and Clathrin-Mediated Endocytosis

(2011) Paulina Aleksandrowicz et al.   JOURNAL OF INFECTIOUS DISEASES

Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells

(2011) H. San-Juan-Vergara et al.   JOURNAL OF VIROLOGY

One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates

(2011) P. W. Denton et al.   JOURNAL OF VIROLOGY

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway

(2011) Nirupama Mulherkar et al.   VIROLOGY

The Actin Cytoskeleton as a Barrier to Virus Infection of Polarized Epithelial Cells

(2011) Elizabeth Delorme-Axford et al.   Viruses-Basel

Quiescent T cells and HIV: an unresolved relationship

(2010) Dimitrios N. Vatakis et al.   IMMUNOLOGIC RESEARCH

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

Respiratory Syncytial Virus-Neutralizing Monoclonal Antibodies Motavizumab and Palivizumab Inhibit Fusion

(2010) K. Huang et al.   JOURNAL OF VIROLOGY

Different Rotavirus Strains Enter MA104 Cells through Different Endocytic Pathways: the Role of Clathrin-Mediated Endocytosis

(2010) M. Gutierrez et al.   JOURNAL OF VIROLOGY

Intersectin-2L Regulates Caveola Endocytosis Secondary to Cdc42-mediated Actin Polymerization

(2009) Irene K. Klein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho GTPases Modulate Entry of Ebola Virus and Vesicular Stomatitis Virus Pseudotyped Vectors

(2009) K. Quinn et al.   JOURNAL OF VIROLOGY

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

The HIV Envelope but Not VSV Glycoprotein Is Capable of Mediating HIV Latent Infection of Resting CD4 T Cells

(2009) Dongyang Yu et al.   PLoS Pathogens

HIV Envelope-CXCR4 Signaling Activates Cofilin to Overcome Cortical Actin Restriction in Resting CD4 T Cells

(2008) Alyson Yoder et al.   CELL

SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway

(2008) Hongliang Wang et al.   CELL RESEARCH

Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes

(2008) M. Barrero-Villar et al.   JOURNAL OF CELL SCIENCE

Cofilin activation in peripheral CD4 T cells of HIV-1 infected patients: a pilot study

(2008) Yuntao Wu et al.   Retrovirology

Susceptibility to virus–cell fusion at the plasma membrane is reduced through expression of HIV gp41 cytoplasmic domains

(2008) Katharina Malinowsky et al.   VIROLOGY