The Newly Discovered Cytokine IL-34 Is Expressed in Gingival Fibroblasts, Shows Enhanced Expression by Pro-Inflammatory Cytokines, and Stimulates Osteoclast Differentiation

IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14brightCD16+ monocytes

(2013) F. Ciccia et al.   RHEUMATOLOGY

Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis

(2012) Seung-Jun Hwang et al.   ARTHRITIS RESEARCH & THERAPY

Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

(2011) M Chemel et al.   ANNALS OF THE RHEUMATIC DISEASES

Paracrine-mediated differentiation and activation of human haematopoietic osteoclast precursor cells by skin and gingival fibroblasts

(2011) J. Costa-Rodrigues et al.   CELL PROLIFERATION

Signal pathways JNK and NF-κB, identified by global gene expression profiling, are involved in regulation of TNFα-induced mPGES-1 and COX-2 expression in gingival fibroblasts

(2010) Tove Båge et al.   BMC GENOMICS

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

(2010) Suwen Wei et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis

(2010) Marc Baud'Huin et al.   JOURNAL OF PATHOLOGY

Proinflammatory cytokines, IL-1β and TNF-α, induce expression of interleukin-34 mRNA via JNK- and p44/42 MAPK-NF-κB pathway but not p38 pathway in osteoblasts

(2010) Hiroyuki Eda et al.   RHEUMATOLOGY INTERNATIONAL

IL-1β and TNF-α Regulate IL-6-type Cytokines in Gingival Fibroblasts

(2009) P. Palmqvist et al.   JOURNAL OF DENTAL RESEARCH

Cytokine responses against periodontal infection: protective and destructive roles

(2009) Yen-Chun G. Liu et al.   PERIODONTOLOGY 2000

Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

(2008) H. Lin et al.   SCIENCE