Polymorphic Cytochrome P450 Enzymes (CYPs) and Their Role in Personalized Therapy

DNA Microarray Technology in the Clinical Environment: The AmpliChip CYP450 Test for CYP2D6 and CYP2C19 Genotyping

(2016) Jose de Leon et al.   CNS SPECTRUMS

CYP2D6*4 allele and breast cancer risk: Is there any association?

(2012) Ana Fernández-Santander et al.   Clinical & Translational Oncology

Functional Genetic Polymorphisms from Phase-II Drug Metabolizing Enzymes

(2012) Sandeep Grover et al.   CNS Neuroscience & Therapeutics

Cytochrome P450 variations in different ethnic populations

(2012) Joseph McGraw et al.   Expert Opinion on Drug Metabolism & Toxicology

Cytochrome P450 1A1 (CYP1A1) gene polymorphisms and ovarian cancer risk: a meta-analysis

(2012) Theodoros N. Sergentanis et al.   MOLECULAR BIOLOGY REPORTS

Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population

(2012) Ran Huo et al.   PLoS One

Reductive activation of 5-fluorodeoxyuridine prodrug possessing azide methyl group by hypoxic X-irradiation

(2011) Kazuhito Tanabe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network

(2011) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse

(2011) S. Shalapour et al.   HAEMATOLOGICA

Sequence variants at CYP1A1–CYP1A2 and AHR associate with coffee consumption

(2011) Patrick Sulem et al.   HUMAN MOLECULAR GENETICS

Prediction of Clopidogrel Low Responders by a Rapid CYP2C19 Activity Test

(2011) Junichi Tazaki et al.   Journal of Atherosclerosis and Thrombosis

Membrane Position of Ibuprofen Agrees with Suggested Access Path Entrance to Cytochrome P450 2C9 Active Site

(2011) Karel Berka et al.   JOURNAL OF PHYSICAL CHEMISTRY A

SDM--a server for predicting effects of mutations on protein stability and malfunction

(2011) C. L. Worth et al.   NUCLEIC ACIDS RESEARCH

Part 2: Pharmacogenetic Variability in Drug Transport and Phase I Anticancer Drug Metabolism

(2011) M. J. Deenen et al.   ONCOLOGIST

CYP2D6and the severity of suicide attempts

(2011) Eva M Peñas-Lledó et al.   PHARMACOGENOMICS

CYP2C19*2 and other genetic variants affecting platelet response to clopidogrel in patients undergoing percutaneous coronary intervention

(2011) George Kassimis et al.   THROMBOSIS RESEARCH

Cytochrome 2C19*17 Allelic Variant, Platelet Aggregation, Bleeding Events, and Stent Thrombosis in Clopidogrel-Treated Patients With Coronary Stent Placement

(2010) Dirk Sibbing et al.   CIRCULATION

Reduced-Function CYP2C19 Genotype and Risk of Adverse Clinical Outcomes Among Patients Treated With Clopidogrel Predominantly for PCI

(2010) Jessica L. Mega et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cardiovascular Risk in Clopidogrel-Treated Patients According to Cytochrome P450 2C19*2 Loss-of-Function Allele or Proton Pump Inhibitor Coadministration

(2010) Jean-Sébastien Hulot et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Cytochrome P450 2C19*2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: a meta-analysis

(2010) F Sofi et al.   PHARMACOGENOMICS JOURNAL

Polymorphism of human cytochrome P450 enzymes and its clinical impact

(2009) Shu-Feng Zhou et al.   DRUG METABOLISM REVIEWS

GeneSigDB—a curated database of gene expression signatures

(2009) Aedín C. Culhane et al.   NUCLEIC ACIDS RESEARCH

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions

(2009) Saskia Preissner et al.   NUCLEIC ACIDS RESEARCH

Antiplatelet therapies and the role of antiplatelet resistance in acute coronary syndrome

(2009) Allison G. Dupont et al.   THROMBOSIS RESEARCH

Pharmacogenetics-Guided Dose Modifications of Antidepressants

(2008) Angela Seeringer et al.   CLINICS IN LABORATORY MEDICINE

Cytochrome P450-Activated Prodrugs: Targeted Drug Delivery

(2008) Kristiina Huttunen et al.   CURRENT MEDICINAL CHEMISTRY

The future (or lack of future) of personalized prescription in psychiatry

(2008) Jose de Leon   PHARMACOLOGICAL RESEARCH

Cytochrome P450 and Chemical Toxicology

(2007) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY