ESAT-6 (EsxA) and TB10.4 (EsxH) Based Vaccines for Pre- and Post-Exposure Tuberculosis Vaccination

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

Analysis of Immune Responses against a Wide Range of Mycobacterium tuberculosis Antigens in Patients with Active Pulmonary Tuberculosis

(2012) Desta Kassa et al.   Clinical and Vaccine Immunology

An update on vaccines for tuberculosis – there is more to it than just waning of BCG efficacy with time

(2012) Marta Romano et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

HspX-mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule

(2012) Jennifer L Taylor et al.   IMMUNOLOGY AND CELL BIOLOGY

Vaccine-Induced Th17 Cells Are Maintained Long-Term Postvaccination as a Distinct and Phenotypically Stable Memory Subset

(2012) Thomas Lindenstrøm et al.   INFECTION AND IMMUNITY

Bioinformatic and Empirical Analysis of Novel Hypoxia-Inducible Targets of the Human Antituberculosis T Cell Response

(2012) H. P. Gideon et al.   JOURNAL OF IMMUNOLOGY

Therapeutic Immunization against Mycobacterium tuberculosis Is an Effective Adjunct to Antibiotic Treatment

(2012) Rhea N. Coler et al.   JOURNAL OF INFECTIOUS DISEASES

Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go?

(2012) Tom H. M. Ottenhoff et al.   PLoS Pathogens

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

SPICE: Exploration and analysis of post-cytometric complex multivariate datasets

(2011) Mario Roederer et al.   CYTOMETRY PART A

Mtb32 is a promising tuberculosis antigen for DNA vaccination in pre- and post-exposure mouse models

(2011) S-S Ahn et al.   GENE THERAPY

Solution Structure of theMycobacterium tuberculosisEsxG·EsxH Complex

(2011) Dariush Ilghari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A multistage tuberculosis vaccine that confers efficient protection before and after exposure

(2011) Claus Aagaard et al.   NATURE MEDICINE

A Booster Vaccine Expressing a Latency-Associated Antigen Augments BCG Induced Immunity and Confers Enhanced Protection against Tuberculosis

(2011) Bappaditya Dey et al.   PLoS One

The ins and outs of Mycobacterium tuberculosis protein export

(2011) Lauren S. Ligon et al.   TUBERCULOSIS

Protein export systems ofMycobacterium tuberculosis: novel targets for drug development?

(2010) Meghan E Feltcher et al.   Future Microbiology

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

(2010) Iñaki Comas et al.   NATURE GENETICS

Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors

(2010) Clifford V. Harding et al.   NATURE REVIEWS MICROBIOLOGY

Hypoxia Induces an Immunodominant Target of Tuberculosis Specific T Cells Absent from Common BCG Vaccines

(2010) Hannah Priyadarshini Gideon et al.   PLoS Pathogens

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

A replication clock for Mycobacterium tuberculosis

(2009) Wendy P Gill et al.   NATURE MEDICINE

Distinct Differences in the Expansion and Phenotype of TB10.4 Specific CD8 and CD4 T Cells after Infection with Mycobacterium tuberculosis

(2009) Truc Thi Kim Thanh Hoang et al.   PLoS One

MVA.85A Boosting of BCG and an Attenuated, phoP Deficient M. tuberculosis Vaccine Both Show Protective Efficacy Against Tuberculosis in Rhesus Macaques

(2009) Frank A. W. Verreck et al.   PLoS One

Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics

(2009) L. J. Abu-Raddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

(2009) H. E. Volkman et al.   SCIENCE

Mycobacterium tuberculosis ESX-1 system-secreted protein ESAT-6 but not CFP10 inhibits human T-cell immune responses

(2009) Buka Samten et al.   TUBERCULOSIS

Evidence for Pore Formation in Host Cell Membranes by ESX-1-Secreted ESAT-6 and Its Role in Mycobacterium marinum Escape from the Vacuole

(2008) J. Smith et al.   INFECTION AND IMMUNITY

Cationic Liposomes Formulated with Synthetic Mycobacterial Cordfactor (CAF01): A Versatile Adjuvant for Vaccines with Different Immunological Requirements

(2008) Else Marie Agger et al.   PLoS One