Neurogenic Detrusor Overactivity Is Associated with Decreased Expression and Function of the Large Conductance Voltage- and Ca2+-Activated K+ Channels

Inhibition of phosphodiesterases relaxes detrusor smooth muscle via activation of the large-conductance voltage- and Ca2+-activated K+ channel

(2012) Wenkuan Xin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca2+-activated K+ channels

(2012) Kiril L. Hristov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Large-conductance calcium-activated potassium channel activity, as determined by whole-cell patch clamp recording, is decreased in urinary bladder smooth muscle cells from male rats with partial urethral obstruction

(2012) Memduh Aydin et al.   BJU INTERNATIONAL

Botulinum toxin injection for lower urinary tract dysfunction

(2012) Yue-Chen Kuo et al.   INTERNATIONAL JOURNAL OF UROLOGY

Large-conductance voltage- and Ca2+-activated K+ channels regulate human detrusor smooth muscle function

(2011) Kiril L. Hristov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Safety and Tolerability Profiles of Anticholinergic Agents Used for the Treatment of Overactive Bladder

(2011) Michael G. Oefelein   DRUG SAFETY

Botulinum toxin A modulates afferent fibers in neurogenic detrusor overactivity

(2011) A. Conte et al.   EUROPEAN JOURNAL OF NEUROLOGY

Large conductance Ca2+-activated K+ channel activation with NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle

(2011) Rupal P. Soder et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of potassium ion channels in detrusor smooth muscle function and dysfunction

(2011) Georgi V. Petkov   Nature Reviews Urology

Effects of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients

(2010) Stephanie Oger et al.   BJU INTERNATIONAL

Adverse Events of Intravesical Botulinum Toxin A Injections for Idiopathic Detrusor Overactivity: Risk Factors and Influence on Treatment Outcome

(2010) Hann-Chorng Kuo et al.   EUROPEAN UROLOGY

BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle

(2009) Jeffrey J. Layne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder

(2009) Franz Sprossmann et al.   FEBS Journal

Role of K+ Channels in Regulating Spontaneous Activity in Detrusor Smooth Muscle In Situ in the Mouse Bladder

(2009) Masa Hayase et al.   JOURNAL OF UROLOGY

Efficacy and Safety of Oxybutynin Chloride Topical Gel for Overactive Bladder: A Randomized, Double-Blind, Placebo Controlled, Multicenter Study

(2009) David R. Staskin et al.   JOURNAL OF UROLOGY

Altered expression of calcium-activated K and Cl channels in detrusor overactivity of rats with partial bladder outlet obstruction

(2008) Longkun Li et al.   BJU INTERNATIONAL

BK Channel Modulators: A Comprehensive Overview

(2008) Antonio Nardi et al.   CURRENT MEDICINAL CHEMISTRY

Gene transfer with a vector expressing Maxi-K from a smooth muscle-specific promoter restores erectile function in the aging rat

(2008) A Melman et al.   GENE THERAPY

Refractory Idiopathic Urge Urinary Incontinence and Botulinum A Injection

(2008) Linda Brubaker et al.   JOURNAL OF UROLOGY