A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests

HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner

(2013) M. Malvaez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC6 Regulates Glucocorticoid Receptor Signaling in Serotonin Pathways with Critical Impact on Stress Resilience

(2012) J. Espallergues et al.   JOURNAL OF NEUROSCIENCE

HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity

(2012) Mitsumasa Kurita et al.   NATURE NEUROSCIENCE

The histone deacetylase inhibitor, sodium butyrate, alleviates cognitive deficits in pre-motor stage PD

(2012) Pallavi Rane et al.   NEUROPHARMACOLOGY

Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity

(2012) Daniel M. Fass et al.   NEUROPHARMACOLOGY

Strain differences in the effects of chronic corticosterone exposure in the hippocampus

(2012) G.E. Hodes et al.   NEUROSCIENCE

Loss of Deacetylation Activity of Hdac6 Affects Emotional Behavior in Mice

(2012) Masahide Fukada et al.   PLoS One

Histone Deacetylase Inhibitors Preserve White Matter Structure and Function during Ischemia by Conserving ATP and Reducing Excitotoxicity

(2011) S. Baltan et al.   JOURNAL OF NEUROSCIENCE

Clozapine and lithium require Caenorhabditis elegans β-arrestin and serum- and glucocorticoid-inducible kinase to affect Daf-16 (Foxo) localization

(2011) Kathrine R. Weeks et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neuroanatomical Profile of Antimaniac Effects of Histone Deacetylases Inhibitors

(2011) Camila O. Arent et al.   MOLECULAR NEUROBIOLOGY

AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice

(2011) Jen Q Pan et al.   NEUROPSYCHOPHARMACOLOGY

Deletion of forebrain glucocorticoid receptors impairs neuroendocrine stress responses and induces depression-like behavior in males but not females

(2011) M.B. Solomon et al.   NEUROSCIENCE

Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition

(2011) Herbert E. Covington et al.   NEUROSCIENCE LETTERS

Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse

(2011) Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behavioral insights from mouse models of forebrain- and amygdala-specific glucocorticoid receptor genetic disruption

(2010) Melinda G. Arnett et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Histone Deacetylase Inhibitor MS-275 Exhibits Poor Brain Penetration: Pharmacokinetic Studies of [11C]MS-275 using Positron Emission Tomography

(2009) Jacob M. Hooker et al.   ACS Chemical Neuroscience

Epigenetic Mechanisms in Psychiatry

(2009) Eric J. Nestler   BIOLOGICAL PSYCHIATRY

Antidepressant Actions of Histone Deacetylase Inhibitors

(2009) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

Altered gene expression of histone deacetylases in mood disorder patients

(2009) Teruyuki Hobara et al.   JOURNAL OF PSYCHIATRIC RESEARCH

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Histone H3 Phosphorylation is Under the Opposite Tonic Control of Dopamine D2 and Adenosine A2A Receptors in Striatopallidal Neurons

(2009) Jesus Bertran-Gonzalez et al.   NEUROPSYCHOPHARMACOLOGY

Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice

(2008) Steven J. Del Signore et al.   Amyotrophic Lateral Sclerosis

Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development

(2008) Jessica L. MacDonald et al.   DEVELOPMENTAL DYNAMICS

Pimelic Diphenylamide 106 Is a Slow, Tight-binding Inhibitor of Class I Histone Deacetylases

(2008) C. James Chou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic Neuroprotective Effects of Lithium and Valproic Acid or Other Histone Deacetylase Inhibitors in Neurons: Roles of Glycogen Synthase Kinase-3 Inhibition

(2008) Y. Leng et al.   JOURNAL OF NEUROSCIENCE

Differential expression of IEG mRNA in rat brain following acute treatment with clozapine or haloperidol: a semi-quantitative RT—PCR study

(2008) MJ Robbins et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model

(2008) H.-L. Feng et al.   NEUROSCIENCE

Chronic microinjection of valproic acid into the nucleus accumbens attenuates amphetamine-induced locomotor activity

(2008) Wha Young Kim et al.   NEUROSCIENCE LETTERS

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

(2007) Joey L. Methot et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS