HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity

An epigenetic blockade of cognitive functions in the neurodegenerating brain

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Epigenetic protein families: a new frontier for drug discovery

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Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs

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Pharmacotherapy for treatment-refractory schizophrenia

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Maternal Influenza Viral Infection Causes Schizophrenia-Like Alterations of 5-HT2A and mGlu2 Receptors in the Adult Offspring

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Multiple models to capture the variability in biological neurons and networks

(2011) Eve Marder et al.   NATURE NEUROSCIENCE

Pharmacological Activation of Group-II Metabotropic Glutamate Receptors Corrects a Schizophrenia-Like Phenotype Induced by Prenatal Stress in Mice

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Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder

(2011) Hamid Mostafavi Abdolmaleky et al.   SCHIZOPHRENIA RESEARCH

Balancing histone methylation activities in psychiatric disorders

(2011) Cyril Jayakumar Peter et al.   TRENDS IN MOLECULAR MEDICINE

Mesolimbic Dopamine Neurons in the Brain Reward Circuit Mediate Susceptibility to Social Defeat and Antidepressant Action

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Schizophrenia: The making of a troubled mind

(2010) David Dobbs   NATURE

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Pharmacogenetic analysis of the mGlu2/3 agonist LY2140023 monohydrate in the treatment of schizophrenia

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Augmentation of atypical antipsychotics with valproic acid. An open-label study for most difficult patients with schizophrenia

(2009) Takefumi Suzuki et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Regional and subcellular distribution of HDAC4 in mouse brain

(2009) Michael J. Darcy et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Epigenetic Modulation of mGlu2 Receptors by Histone Deacetylase Inhibitors in the Treatment of Inflammatory Pain

(2009) S. Chiechio et al.   MOLECULAR PHARMACOLOGY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Modeling “psychosis” in vitro by inducing disordered neuronal network activity in cortical brain slices

(2009) George K. Aghajanian   PSYCHOPHARMACOLOGY

Psychedelics and schizophrenia

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Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

Evidence for the Role of Metabotropic Glutamate (mGlu)2 Not mGlu3 Receptors in the Preclinical Antipsychotic Pharmacology of the mGlu2/3 Receptor Agonist (-)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic Acid (LY404039)

(2008) M. J. Fell et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Identification of a serotonin/glutamate receptor complex implicated in psychosis

(2008) Javier González-Maeso et al.   NATURE

Decoding the Epigenetic Language of Neuronal Plasticity

(2008) Emiliana Borrelli et al.   NEURON

Antipsychotic Drugs: Comparison in Animal Models of Efficacy, Neurotransmitter Regulation, and Neuroprotection

(2008) J. A. Lieberman et al.   PHARMACOLOGICAL REVIEWS

Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation

(2008) E. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serotonin research: contributions to understanding psychoses

(2008) M GEYER et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Complementary roles for histone deacetylases 1, 2, and 3 in differentiation of pluripotent stem cells

(2007) Glen W. Humphrey et al.   DIFFERENTIATION