Overexpression of the Toll-Like Receptor (TLR) Signaling Adaptor MYD88, but Lack of Genetic Mutation, in Myelodysplastic Syndromes

Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1

(2012) J. Fang et al.   BLOOD

STAT3-Driven Upregulation of TLR2 Promotes Gastric Tumorigenesis Independent of Tumor Inflammation

(2012) Hazel Tye et al.   CANCER CELL

Validation of a Prognostic Model and the Impact of Mutations in Patients With Lower-Risk Myelodysplastic Syndromes

(2012) Rafael Bejar et al.   JOURNAL OF CLINICAL ONCOLOGY

MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

(2012) Steven P. Treon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome

(2011) M. S. Kumar et al.   BLOOD

Absence of MYD88 gene mutation in acute leukemias and multiple myelomas

(2011) Eun M. Je et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Chronic Exposure to a TLR Ligand Injures Hematopoietic Stem Cells

(2011) B. L. Esplin et al.   JOURNAL OF IMMUNOLOGY

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

Innate Immune Signaling in the Myelodysplastic Syndromes

(2010) Daniel T. Starczynowski et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Oncogenically active MYD88 mutations in human lymphoma

(2010) Vu N. Ngo et al.   NATURE

Erythroid Progenitor Cells Expanded from Peripheral Blood without Mobilization or Preselection: Molecular Characteristics and Functional Competence

(2010) Claudia Filippone et al.   PLoS One

PKC-α controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells

(2009) Christelle Langlet et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes

(2009) Simone V. da Costa et al.   LEUKEMIA RESEARCH

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

(2009) Daniel T Starczynowski et al.   NATURE MEDICINE

Myelodysplastic Syndromes

(2009) Ayalew Tefferi et al.   NEW ENGLAND JOURNAL OF MEDICINE

TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer

(2009) M Szajnik et al.   ONCOGENE

ATM mediates constitutive NF-κB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

(2008) J Grosjean-Raillard et al.   ONCOGENE

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

(2008) J. B. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA