Mitochondrial Function in Human Neuroblastoma Cells Is Up-Regulated and Protected by NQO1, a Plasma Membrane Redox Enzyme

Bioenergetics Pathways and Therapeutic Resistance in Gliomas: Emerging Role of Mitochondria

(2011) Corinne E. Griguer et al.   CURRENT PHARMACEUTICAL DESIGN

The antioxidant Trolox helps recovery from the familial Parkinson's disease-specific mitochondrial deficits caused by PINK1- and DJ-1-deficiency in dopaminergic neuronal cells

(2011) Jung Hee Shim et al.   MITOCHONDRION

NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels

(2011) Roman H. Haefeli et al.   PLoS One

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

Inhibitors of NQO1: Identification of compounds more potent than dicoumarol without associated off-target effects

(2010) Katherine Ann Scott et al.   BIOCHEMICAL PHARMACOLOGY

The plasma membrane redox system is impaired by amyloid β-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice

(2010) Dong-Hoon Hyun et al.   EXPERIMENTAL NEUROLOGY

Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

(2010) Lu Zhu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer

(2010) B A Patrick et al.   ONCOGENE

Cruciferous Dithiolethione-Mediated Coordinated Induction of Total Cellular and Mitochondrial Antioxidants and Phase 2 Enzymes in Human Primary Cardiomyocytes: Cytoprotection Against Oxidative/Electrophilic Stress and Doxorubicin Toxicity

(2009) Hong Zhu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

(2009) Erich B. Tahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

(2009) Tae Gen Son et al.   JOURNAL OF NEUROCHEMISTRY

Protective Effects of Neurotrophic Factor–Secreting Cells in a 6-OHDA Rat Model of Parkinson Disease

(2009) Ofer Sadan et al.   STEM CELLS AND DEVELOPMENT

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Potent induction of total cellular GSH and NQO1 as well as mitochondrial GSH by 3H-1,2-dithiole-3-thione in SH-SY5Y neuroblastoma cells and primary human neurons: Protection against neurocytotoxicity elicited by dopamine, 6-hydroxydopamine, 4-hydroxy-2-nonenal, or hydrogen peroxide

(2008) Zhenquan Jia et al.   BRAIN RESEARCH

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Potent Induction of Total Cellular and Mitochondrial Antioxidants and Phase 2 Enzymes by Cruciferous Sulforaphane in Rat Aortic Smooth Muscle Cells: Cytoprotection Against Oxidative and Electrophilic Stress

(2008) Hong Zhu et al.   Cardiovascular Toxicology

Role of Mitochondrial Dysfunction in Insulin Resistance

(2008) Jeong-a Kim et al.   CIRCULATION RESEARCH

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON