Adaptive and Specialised Transcriptional Responses to Xenobiotic Stress in Caenorhabditis elegans Are Regulated by Nuclear Hormone Receptors

Analysis of C. elegans NR2E nuclear receptors defines three conserved clades and ligand-independent functions

(2012) Katherine P Weber et al.   BMC EVOLUTIONARY BIOLOGY

The Transcriptional Response of Caenorhabditis elegans to Ivermectin Exposure Identifies Novel Genes Involved in the Response to Reduced Food Intake

(2012) Steven T. Laing et al.   PLoS One

A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue

(2011) Rebecca A. Green et al.   CELL

Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art

(2011) Lucie Stejskalova et al.   CURRENT DRUG METABOLISM

A Muscle-Specific p38 MAPK/Mef2/MnSOD Pathway Regulates Stress, Motor Function, and Life Span in Drosophila

(2011) Alysia Vrailas-Mortimer et al.   DEVELOPMENTAL CELL

Application of physiologically based modelling and transcriptomics to probe the systems toxicology of aldicarb for Caenorhabditis elegans (Maupas 1900)

(2011) Jodie F. Wren et al.   ECOTOXICOLOGY

Transcriptional regulation of xenobiotic detoxification in Drosophila

(2011) J. R. Misra et al.   GENES & DEVELOPMENT

The Response ofCaenorhabditis elegansto Hydrogen Sulfide and Hydrogen Cyanide

(2011) Mark W. Budde et al.   GENETICS

The MDT-15 Subunit of Mediator Interacts with Dietary Restriction to Modulate Longevity and Fluoranthene Toxicity in Caenorhabditis elegans

(2011) Jennifer Schleit et al.   PLoS One

Genotoxicity and apoptosis in Drosophila melanogaster exposed to benzene, toluene and xylene: Attenuation by quercetin and curcumin

(2011) Mahendra P. Singh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR

(2010) Antonia H. Tolson et al.   ADVANCED DRUG DELIVERY REVIEWS

Characterization of the xenobiotic response ofCaenorhabditis elegansto the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites

(2010) Steven T. Laing et al.   BIOCHEMICAL JOURNAL

Nuclear hormone receptors in nematodes: Evolution and function

(2010) Stefan Taubert et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Allyl Isothiocyanate that Induces GST and UGT Expression Confers Oxidative Stress Resistance on C. elegans, as Demonstrated by Nematode Biosensor

(2010) Koichi Hasegawa et al.   PLoS One

Genome-Wide Gene Expression Analysis in Response to Organophosphorus Pesticide Chlorpyrifos and Diazinon in C. elegans

(2010) Ana Viñuela et al.   PLoS One

Xenobiotic Metabolism, Disposition, and Regulation by Receptors: From Biochemical Phenomenon to Predictors of Major Toxicities

(2010) C. J. Omiecinski et al.   TOXICOLOGICAL SCIENCES

Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1

(2009) Sang-Kyu Park et al.   AGING CELL

The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis

(2009) M. A. Horner et al.   GENES & DEVELOPMENT

Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone

(2009) Aaron J. Przybysz et al.   MECHANISMS OF AGEING AND DEVELOPMENT

WormBase: a comprehensive resource for nematode research

(2009) Todd W. Harris et al.   NUCLEIC ACIDS RESEARCH

Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor

(2008) Christoph Köhle et al.   BIOCHEMICAL PHARMACOLOGY

Comparative analysis of function and interaction of transcription factors in nematodes: Extensive conservation of orthology coupled to rapid sequence evolution

(2008) Wilfried Haerty et al.   BMC GENOMICS

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

Characterisation by RNAi of pioneer genes expressed in the dorsal pharyngeal gland cell of Heterodera glycines and the effects of combinatorial RNAi

(2008) M. Bakhetia et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression

(2008) Baby P. S. Chakrapani et al.   JOURNAL OF BIOSCIENCES

Caenorhabditis elegans nuclear receptors: insights into life traits

(2008) Daniel B. Magner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Mediator Subunit MDT-15 Confers Metabolic Adaptation to Ingested Material

(2008) Stefan Taubert et al.   PLoS Genetics

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

(2007) Jean-Marc Pascussi et al.   Annual Review of Pharmacology and Toxicology