TRIM11 Negatively Regulates IFNβ Production and Antiviral Activity by Targeting TBK1

The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-  Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3

(2014) R. Higgs et al.   JOURNAL OF IMMUNOLOGY

RING Finger Protein 11 Targets TBK1/IKKi Kinases to Inhibit Antiviral Signaling

(2013) Soratree Charoenthongtrakul et al.   PLoS One

TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1

(2012) Meng Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tripartite Motif-Containing Protein 38 Negatively Regulates TLR3/4- and RIG-I-Mediated IFN-  Production and Antiviral Response by Targeting NAP1

(2012) W. Zhao et al.   JOURNAL OF IMMUNOLOGY

The E3 ubiquitin ligase TRIM11 mediates the degradation of congenital central hypoventilation syndrome-associated polyalanine-expanded PHOX2B

(2012) Sara Parodi et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4

(2012) Jun Cui et al.   NATURE IMMUNOLOGY

Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins

(2011) Taro Kawai et al.   EMBO Molecular Medicine

Tripartite Motif-Containing Protein 28 Is a Small Ubiquitin-Related Modifier E3 Ligase and Negative Regulator of IFN Regulatory Factor 7

(2011) Q. Liang et al.   JOURNAL OF IMMUNOLOGY

Functional Dissection of the TBK1 Molecular Network

(2011) Adriana Goncalves et al.   PLoS One

Tripartite-motif proteins and innate immune regulation

(2010) Finlay W McNab et al.   CURRENT OPINION IN IMMUNOLOGY

Glycogen Synthase Kinase 3β Regulates IRF3 Transcription Factor-Mediated Antiviral Response via Activation of the Kinase TBK1

(2010) Cao-Qi Lei et al.   IMMUNITY

TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases

(2010) Kislay Parvatiyar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absence of SHIP-1 Results in Constitutive Phosphorylation of Tank-Binding Kinase 1 and Enhanced TLR3-Dependent IFN-β Production

(2010) Joan Ní Gabhann et al.   JOURNAL OF IMMUNOLOGY

The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3

(2010) Hwijin Kim et al.   NATURE IMMUNOLOGY

Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors

(2010) Rowan Higgs et al.   PLoS One

TRIM Proteins: Another Class of Viral Victims

(2010) M. Munir   Science Signaling

Negative Regulation of MAVS-Mediated Innate Immune Response by PSMA7

(2009) Y. Jia et al.   JOURNAL OF IMMUNOLOGY

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon

(2009) Chen Wang et al.   NATURE IMMUNOLOGY

PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4

(2009) Fuping You et al.   NATURE IMMUNOLOGY

Human TRIM Gene Expression in Response to Interferons

(2009) Laetitia Carthagena et al.   PLoS One

Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system

(2008) T. C. Tuoc et al.   GENES & DEVELOPMENT

NLRX1 is a regulator of mitochondrial antiviral immunity

(2008) Chris B. Moore et al.   NATURE

TRIM E3 Ligases Interfere with Early and Late Stages of the Retroviral Life Cycle

(2008) Pradeep D. Uchil et al.   PLoS Pathogens