Article
Environmental Sciences
Iryna Rehan, Pedro M. Felix, Vanessa Morgado, Ricardo J. N. Bettencourt da Silva, Carla Palma
Summary: Sea cucumbers serve as indicators of metal contamination in sea bottoms due to their low mobility and feeding behavior. Comparing contaminations of specimens from different locations, habitats, and/or organs provides insights into contamination processes and differences. However, the interpretation of these data is affected by variability in contamination levels, uncertainty in tissue analysis, and complex correlations in mass fractions estimated using the same calibration of the instrumental method. This study introduces a novel tool that considers these factors to reliably compare contamination levels of biota and obtain undisputable information on the studied system.
Article
Biochemistry & Molecular Biology
Hanbing Jiang, Siying Zhu, Bin Wu, Yinyin Su, Qiming Wang, Yonghua Lei, Qiuju Shao, Yun Gao, Ke Gao, Guojun Wu
Summary: This study investigated the molecular mechanism of liensinine (LIEN) in the management of bladder cancer (BCa). The findings suggest that LIEN may promote senescence and inhibit proliferation of BCa by inhibiting the CDK2/4 and PI3K/AKT pathways.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Environmental Sciences
Alexey Vladimirovich Galchenko, Elizaveta Ilinichna Sidorova, Anastasia Alekseevna Sherstneva, Andrew Anatolevich Skalny, Julia Nikolaevna Lobanova
Summary: The study aimed to compare the toxic elements composition in people's hair from different regions of the world. The results showed that the concentrations of toxic elements in students' hair were generally within normal ranges, but there was a significantly higher level of tin in hair from Russia, Moldova, and Ukraine. This indicates a need for further large-scale environmental studies due to the deteriorating environmental situation worldwide.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Mathematics
Xunfa Lu, Zhitao Ye, Kin Keung Lai, Hairong Cui, Xiao Lin
Summary: This paper applies a new time-varying causality test to examine the causalities in prices and volatilities between the Chinese mainland stock market and the Hong Kong stock market. The empirical results show significant time-varying causalities, and the implications of the results are discussed.
Article
Fisheries
Luke Batts, Coilin Minto, Hans Gerritsen, Deirdre Brophy
Summary: Stage-based assessment models provide a middle ground between aggregate and compositional models. This study compares the capabilities of two theoretically different stage-based assessment approaches and evaluates their performance on simulated and real stock scenarios.
CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES
(2022)
Article
Biotechnology & Applied Microbiology
Xiaoye Shen, Yuan Su, Zi Hua, Hongmei Zhu, Gulhan Unlu, Carolyn Ross, Manoella Mendoza, Ines Hanrahan, Juming Tang, Mei-Jun Zhu
Summary: This study evaluated the cross-contamination of Listeria monocytogenes during apple wax coating and found that the waxing process reduced the L. monocytogenes count on apples. The study also showed that the waxing brush used during coating could transfer L. monocytogenes to other apples. These findings highlight the importance of controlling L. monocytogenes on wax-coated apples.
Article
Multidisciplinary Sciences
Tatiana F. P. de Oliveira, A. F. Antonio Junior, Anapolino m. de Oliveira, Marcelo F. Camargos, Marcos B. Heinemann
Summary: This study analyzed the genetic relationships between different types of viral contaminants found in cell cultures, calf serum, and standard strains. The results showed that the contaminants included Bovine viral diarrhea virus, Hobi-like viruses, and Classical swine fever virus.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2023)
Article
Ecology
Kamal Khosravi Aqdam, Nafiseh Yaghmaeian Mahabadi, Hassan Ramezanpour, Salar Rezapour, Zohreh Mosleh, Ehsan Zare
Summary: This study compared the uncertainty spatial distribution of soil organic carbon (SOC) stocks in different land uses. The highest uncertainty was found in dry farming, and the interactive effects between soil erodibility factor, sand, and EC were identified as the key factors influencing the uncertainty of SOC stocks.
JOURNAL OF ARID ENVIRONMENTS
(2022)
Article
Chemistry, Analytical
Eman I. El-Kimary, Mohammed A. Korany, Ahmed E. Issa, Mohamed G. Basuny
Summary: This work describes a fast and simple HPLC-DAD method for the simultaneous microdetermination of nine penicillin drugs to study cross contamination of non-penicillin pharmaceutical dosage forms. The method showed good accuracy, precision, and sensitivity, making it suitable for routine quality control to study and determine cross contamination.
MICROCHEMICAL JOURNAL
(2023)
Article
Agronomy
Jose A. Gomez, Lizardo Reyna-Bowen, Pilar Fernandez Rebollo, Maria-Auxiliadora Soriano
Summary: This study evaluates the soil organic carbon and stock in two olive orchards with different tree densities. The results indicate the potential for a significant increase in soil organic carbon and stock in olive orchards at higher tree densities when combined with temporary cover crops and mulch of chopped pruning residues.
Article
Chemistry, Physical
C-Y Hsu, J. Stodolna, P. Todeschini, F. Delabrouille, V Barnier, B. Radiguet, F. Christien
Summary: The study successfully quantified the degree of phosphorus interfacial segregation in the sample by cross comparing four different techniques, which showed reasonable agreement.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Physical
Zi Wang, Shuang Li, Xinke Zhang, Jiaye Su
Summary: This study investigates the influence of channel shape on water transport through graphene channels using molecular dynamics simulations. The results show that the water flux increases monotonously when the channel shape changes from two-dimensional to three-dimensional, due to the reduction in water translocation time, and this is consistent with the calculation by the Navier-Stokes equation.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Environmental Sciences
Mohsen Jalali, Ziba Hurseresht, Faranak Ranjbar
Summary: This study evaluated the effectiveness of eight chemical agents in mobilizing five potentially toxic elements in contaminated soils and analyzed the influence of soil properties on element extractability. The results showed that pH and equivalent calcium carbonate were the most influential parameters in predicting element extractability.
ENVIRONMENTAL EARTH SCIENCES
(2022)
Article
Chemistry, Applied
Jianzhou Qu, Yuyue Zhong, Li Ding, Xingxun Liu, Shutu Xu, Dongwei Guo, Andreas Blennow, Jiquan Xue
Summary: The study highlights the relationship between kernel moisture content and dehydration rate of maize inbred lines, as well as the differential expression of starch biosynthetic genes. Specifically, the increased expression of certain genes in inbred lines with fast dehydration rates may lead to the synthesis of amylose with low molecular weight and amylopectin with low content of amylopectin chains, contributing to their high retrogradation rates.
Article
Food Science & Technology
Yuanyuan Zhang, Cong Zhou, Anthony Bassey, Li Bai, Yeru Wang, Keping Ye
Summary: This study used quantitative exposure assessment to analyze the transfer risk of L. monocytogenes from raw pork to RTE ham. The results showed that increasing the temperature of cleaning water can gradually reduce the transfer rates. Lowering the initial contamination level of raw meat and using tap water of higher temperature to clean the cutting boards were observed to be effective in reducing the risk of cross-contamination of L. monocytogenes in meat products.
Article
Public, Environmental & Occupational Health
Dirk Taeger, Katharina Wichert, Martin Lehnert, Swaantje Casjens, Beate Pesch, Daniel G. Weber, Thomas Bruening, Georg Johnen, Thomas Behrens
Summary: This study aimed to estimate the lung cancer and mesothelioma incidence risk in men with benign asbestos-related lung or pleural diseases. The results showed a significant association between pleural plaques and increased risk for mesothelioma, while no significant association was found for lung cancer.
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
(2022)
Article
Oncology
Ann Olsson, Neela Guha, Liacine Bouaoun, Hans Kromhout, Susan Peters, Jack Siemiatycki, Vikki Ho, Per Gustavsson, Paolo Boffetta, Roel Vermeulen, Thomas Behrens, Thomas Bruening, Benjamin Kendzia, Pascal Guenel, Daniele Luce, Stefan Karrasch, Heinz-Erich Wichmann, Dario Consonni, Maria Teresa Landi, Neil E. Caporaso, Franco Merletti, Dario Mirabelli, Lorenzo Richiardi, Karl-Heinz Joeckel, Wolfgang Ahrens, Hermann Pohlabeln, Adonina Tardon, David Zaridze, John K. Field, Jolanta Lissowska, Beata Swiatkowska, John R. McLaughlin, Paul A. Demers, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Tamas Pandics, Eleonora Fabianova, Dana Mates, Francesco Forastiere, Bas Bueno-de-Mesquita, Joachim Schuez, Kurt Straif
Summary: This study investigated the association between occupational exposure to PAH and lung cancer risk. The results showed an elevated risk of lung cancer among both men and women with PAH exposure. The study also found joint effects between PAH and smoking. However, more recent studies did not show an increased risk of lung cancer associated with PAH.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Environmental Sciences
Benedikt Ringbeck, Daniel Bury, Atsuko Ikeda-Araki, Yu Ait Bamai, Rahel Mesfin Ketema, Chihiro Miyashita, Thomas Bruening, Reiko Kishi, Holger M. Koch
Summary: Nonylphenol (NP) exposure in 7-year-old Japanese children was investigated using human biomonitoring data. The study found that OH-NP and oxo-NP are effective biomarkers for measuring NP exposure. The NP daily intakes in children were close to but lower than the current provisional tolerable daily intake. Additionally, a weak association between urinary OH-NP and oxidative stress biomarkers was observed.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Public, Environmental & Occupational Health
Lisa Gamrad-Streubel, Lisa-Marie Haase, Katharina K. Rudolph, Katrin Ruhle, Annette M. Bachand, Lori Crawford, Kenneth A. Mundt, Juergen Buenger, Dirk Pallapies, Dirk Taeger, Swaantje Casjens, Anja Molkenthin, Savo Neumann, Joerg Giesen, Volker Neumann, Thomas Bruening, Thomas Birk
Summary: The German authorities reassessed the occupational exposure limits for nitrogen oxides and diesel exhaust. A clinical cross-sectional study among salt and potash underground workers exposed to these substances at relatively high levels found no evidence of acute effects on workers' health.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2022)
Article
Oncology
T. Gambichler, C. Finis, N. Abu Rached, C. H. Scheel, J. C. Becker, K. Lang, H. U. Kafferlein, T. Bruning, N. Abolmaali, L. Susok
Summary: The study investigated the protein expression of DNA mismatch repair (MMR) proteins in patients with cutaneous melanoma (CM) receiving immune checkpoint inhibitor (ICI) therapy. Immunohistochemistry was performed on tumor tissue of 50 patients, and reduced MMR protein expression was observed in 16% of patients. Baseline neutrophil/lymphocyte ratio and reduced intratumoral MMR protein expression were significantly associated with favorable treatment response. However, further validation is required in larger patient cohorts.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Oncology
Thomas Behrens, Calvin Ge, Roel Vermeulen, Benjamin Kendzia, Ann Olsson, Joachim Schuez, Hans Kromhout, Beate Pesch, Susan Peters, Luetzen Portengen, Per Gustavsson, Dario Mirabelli, Pascal Guenel, Daniele Luce, Dario Consonni, Neil E. Caporaso, Maria Teresa Landi, John K. Field, Stefan Karrasch, Heinz-Erich Wichmann, Jack Siemiatycki, Marie-Elise Parent, Lorenzo Richiardi, Lorenzo Simonato, Karl-Heinz Joeckel, Wolfgang Ahrens, Hermann Pohlabeln, Guillermo Fernandez-Tardon, David Zaridze, John R. McLaughlin, Paul A. Demers, Beata Swiatkowska, Jolanta Lissowska, Tamas Pandics, Eleonora Fabianova, Dana Mates, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paolo Boffetta, Bas Bueno-de-Mesquita, Francesco Forastiere, Kurt Straif, Thomas Bruening
Summary: Limited evidence exists regarding the exposure-effect relationship between lung-cancer risk and hexavalent chromium (Cr(VI)) or nickel. This study found that occupational exposure to Cr(VI) and nickel was associated with lung-cancer risks, particularly in men. In men, the highest quartile of cumulative exposure to CR(VI) and nickel were both significantly associated with increased odds ratios for lung cancer.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Mehdi Manoochehri, Nasim Borhani, Clarissa Gerhaeuser, Yassen Assenov, Maximilian Schoenung, Thomas Hielscher, Brock C. Christensen, Min Kyung Lee, Hermann-Josef Grone, Daniel B. Lipka, Thomas Bruening, Hiltrud Brauch, Yon-Dschun Ko, Ute Hamann
Summary: Noninvasive detection of aberrant DNA methylation could provide invaluable biomarkers for earlier detection of triple-negative breast cancer (TNBC), aiding clinicians in easier and more efficient treatment options.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Chemistry, Analytical
Sonja A. Wrobel, Daniel Bury, Vladimir N. Belov, Jan M. Klenk, Bernhard Hauer, Heiko Hayen, Anderson J. Martino-Andrade, Holger M. Koch, Thomas Bruening, Heiko U. Kaefferlein
Summary: We have developed a specific and robust analytical method to analyze the most important neonicotinoids and their metabolites in human urine. The method was successfully validated and applied to quantify these compounds in individuals from the general population in Germany and pregnant women from Brazil with no known occupational exposures to neonicotinoids.
ANALYTICA CHIMICA ACTA
(2023)
Article
Allergy
Michal Gina, Katharina Wichert, Gerald Kutz, Thomas Bruening, Manige Fartasch
Summary: This study aimed to evaluate whether the use of protective creams prior to wearing liquid-proof gloves can mitigate the occlusion effect and skin sensitivity. The results showed that the use of protective creams did not alleviate the occlusion effect, and some creams may have negative effects on the skin barrier function and increase sensitivity.
CONTACT DERMATITIS
(2023)
Article
Allergy
Michal Gina, Katharina Wichert, Birgit Pieper, Thomas Behrens, Thomas Bruening, Manige Fartasch
Summary: This study compared the effects of using a shorter duration of a grit-containing cleanser and a longer duration of a mild cleanser on skin damage. The results showed that the shorter duration of the grit-containing cleanser resulted in more significant damage to the skin barrier, while the longer duration of the mild cleanser caused less damage.
CONTACT DERMATITIS
(2023)
Article
Biology
Hans-Peter Rihs, Swaantje Casjens, Irina Raiko, Jens Kollmeier, Martin Lehnert, Kerstin Noefer, Kerstin May-Taube, Nina Kaiser, Dirk Taeger, Thomas Behrens, Thomas Bruening, Georg Johnen
Summary: Mesothelin is a biomarker for malignant mesothelioma, and its concentration is influenced by genetic variants. This study found that four genetic variants were associated with increased mesothelin concentrations, providing useful insight into high values of mesothelin protein in healthy individuals and improving diagnostic procedures.
Article
Environmental Sciences
Alison Connolly, Holger M. Koch, Daniel Bury, Stephan Koslitz, Marike Kolossa-Gehring, Andre Conrad, Aline Murawski, James A. McGrath, Michelle Leahy, Thomas Bruening, Marie A. Coggins
Summary: Glyphosate-based pesticides are widely used worldwide, and a study on farm and non-farm families' exposure to glyphosate found relatively low exposure levels, consistent with previous research. The results contribute to our understanding of glyphosate exposures in different demographic groups and are important for the re-evaluation of glyphosate.
Article
Environmental Sciences
Sonja A. Wrobel, Stephan Koslitz, Vladimir N. Belov, Daniel Bury, Heiko Hayen, Thomas Bruening, Holger M. Koch, Heiko U. Kaefferlein
Summary: This study developed and validated an analytical method to detect the metabolites of neonicotinoid insecticides in human urine. The results showed that the main metabolite in human urine was 6-chloronicotinic acid glycine, but the specific source of exposure remained unclear.
ENVIRONMENTAL RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Dirk Taeger, Stephan Koslitz, Heiko U. Kaefferlein, Tim Pelzl, Birgit Heinrich, Dietmar Breuer, Tobias Weiss, Volker Harth, Thomas Behrens, Thomas Bruening
Summary: This study assessed the levels of polycyclic aromatic hydrocarbons (PAH) during firefighting operations in Germany using biomonitoring methods. The results showed that properly applied protective clothing and wearing of self-contained breathing apparatus (SCBA) can significantly reduce PAH exposure levels. However, there might still be individual situations in which PAH are increasingly incorporated, and the possibility of an individual increased cancer risk cannot be completely ruled out.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)