标题
A New Class of Small Molecule Inhibitor of BMP Signaling
作者
关键词
Kinase inhibitors, Embryos, Phosphorylation, BMP signaling, Hydrogen bonding, In vitro kinase assay, Zebrafish, Tyrosine kinases
出版物
PLoS One
Volume 8, Issue 4, Pages e62721
出版商
Public Library of Science (PLoS)
发表日期
2013-05-02
DOI
10.1371/journal.pone.0062721
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inhibition of Bone Morphogenetic Protein Signaling Reduces Vascular Calcification and Atherosclerosis
- (2012) Matthias Derwall et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Crizotinib for ALK-Rearranged Non-Small Cell Lung Cancer: A New Targeted Therapy for a New Target
- (2012) L. Gandhi et al. CLINICAL CANCER RESEARCH
- Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva
- (2012) Apirat Chaikuad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 3,5-Diaryl-2-aminopyridines as a Novel Class of Orally Active Antimalarials Demonstrating Single Dose Cure in Mice and Clinical Candidate Potential
- (2012) Yassir Younis et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting the TGFβ signalling pathway in disease
- (2012) Rosemary J. Akhurst et al. NATURE REVIEWS DRUG DISCOVERY
- Maternal and Zygotic Control of Zebrafish Dorsoventral Axial Patterning
- (2011) Yvette G. Langdon et al. Annual Review of Genetics
- Pharmacological Suppression of Hepcidin Increases Macrophage Cholesterol Efflux and Reduces Foam Cell Formation and Atherosclerosis
- (2011) Omar Saeed et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats
- (2011) I. Theurl et al. BLOOD
- Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation
- (2011) A. U. Steinbicker et al. BLOOD
- BMP4 Promotes Prostate Tumor Growth in Bone through Osteogenesis
- (2011) Y.-C. Lee et al. CANCER RESEARCH
- The specificities of small molecule inhibitors of the TGFß and BMP pathways
- (2011) Janis Vogt et al. CELLULAR SIGNALLING
- The bone morphogenetic protein–hepcidin axis as a therapeutic target in inflammatory bowel disease
- (2011) Lijian Wang et al. INFLAMMATORY BOWEL DISEASES
- Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)
- (2011) J. Jean Cui et al. JOURNAL OF MEDICINAL CHEMISTRY
- SNW1 Is a Critical Regulator of Spatial BMP Activity, Neural Plate Border Formation, and Neural Crest Specification in Vertebrate Embryos
- (2011) Mary Y. Wu et al. PLOS BIOLOGY
- Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists
- (2010) JE Cannon et al. BRITISH JOURNAL OF PHARMACOLOGY
- Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells
- (2010) J.H. Boergermann et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- High-throughput production of human proteins for crystallization: The SGC experience
- (2010) Pavel Savitsky et al. JOURNAL OF STRUCTURAL BIOLOGY
- Inherited human diseases of heterotopic bone formation
- (2010) Eileen M. Shore et al. Nature Reviews Rheumatology
- BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model
- (2010) SongTing Shi et al. NEUROBIOLOGY OF DISEASE
- In VivoStructure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors
- (2009) Jijun Hao et al. ACS Chemical Biology
- Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2
- (2009) Stephen Hilton et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Applications of small molecule BMP inhibitors in physiology and disease
- (2009) Charles C. Hong et al. CYTOKINE & GROWTH FACTOR REVIEWS
- TGF-β Superfamily Signaling in Embryonic Development and Homeostasis
- (2009) Mary Y. Wu et al. DEVELOPMENTAL CELL
- Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors
- (2008) Gregory D. Cuny et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- BMP-2/4 and BMP-6/7 Differentially Utilize Cell Surface Receptors to Induce Osteoblastic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells
- (2008) Karen Lavery et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BMP type I receptor inhibition reduces heterotopic ossification
- (2008) Paul B Yu et al. NATURE MEDICINE
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