CLL Cells Respond to B-Cell Receptor Stimulation with a MicroRNA/mRNA Signature Associated with MYC Activation and Cell Cycle Progression

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

Cellular origin and pathophysiology of chronic lymphocytic leukemia

(2012) Marc Seifert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

(2012) Shauna A Henley et al.   Cell Division

miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

(2011) Jong-Kook Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells

(2011) S. Krysov et al.   BLOOD

The microRNA body map: dissecting microRNA function through integrative genomics

(2011) Pieter Mestdagh et al.   NUCLEIC ACIDS RESEARCH

The lymph node microenvironment promotes B-cell receptor signaling, NF- B activation, and tumor proliferation in chronic lymphocytic leukemia

(2010) Y. Herishanu et al.   BLOOD

Antigens in chronic lymphocytic leukemia—Implications for cell origin and leukemogenesis

(2010) Anders Rosén et al.   SEMINARS IN CANCER BIOLOGY

Polymorphic Cis- and Trans-Regulation of Human Gene Expression

(2010) Vivian G. Cheung et al.   PLOS BIOLOGY

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406

(2009) M. P. Quiroga et al.   BLOOD

Down-regulation of CXCR4 and CD62L in Chronic Lymphocytic Leukemia Cells Is Triggered by B-Cell Receptor Ligation and Associated with Progressive Disease

(2009) A. Vlad et al.   CANCER RESEARCH

Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA

(2009) B. Stamatopoulos et al.   HAEMATOLOGICA

A Novel POK Family Transcription Factor, ZBTB5, Represses Transcription ofp21CIP1Gene

(2009) Dong-In Koh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence

(2009) N Darzentas et al.   LEUKEMIA

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors

(2009) P Mestdagh et al.   ONCOGENE

Brx Mediates the Response of Lymphocytes to Osmotic Stress Through the Activation of NFAT5

(2009) T. Kino et al.   Science Signaling

A novel and universal method for microRNA RT-qPCR data normalization

(2009) Pieter Mestdagh et al.   GENOME BIOLOGY

BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells

(2008) A. Guarini et al.   BLOOD

High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation

(2008) J. A. Burger et al.   BLOOD

Prognostic markers in chronic lymphocytic leukemia: A comprehensive review

(2008) Femke Van Bockstaele et al.   BLOOD REVIEWS

High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA

(2008) Pieter Mestdagh et al.   NUCLEIC ACIDS RESEARCH