Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

(2012) L. Pilotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

(2011) Daniel Zwilling et al.   CELL

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

(2010) David J. Bonda et al.   REDOX REPORT

Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus

(2010) Koji Ohira et al.   Molecular Brain

Elevated basal cortisol level predicts lower hippocampal volume and cognitive decline in Alzheimer’s disease

(2009) Chi-Wei Huang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Proinflammatory cytokine interferon-γ increases induction of indoleamine 2,3-dioxygenase in monocytic cells primed with amyloid β peptide 1-42: implications for the pathogenesis of Alzheimer’s disease

(2009) Akiko Yamada et al.   JOURNAL OF NEUROCHEMISTRY

Identification and characterization of novel variants of the tryptophan 2,3-dioxygenase gene: Differential regulation in the mouse nervous system during development

(2009) Masaaki Kanai et al.   NEUROSCIENCE RESEARCH

The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons

(2009) Abdur Rahman et al.   PLoS One

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

(2009) Masaaki Kanai et al.   Molecular Brain

Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer disease

(2008) Antonio Macchiarulo et al.   AMINO ACIDS

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY