ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17

Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish

(2012) Sa Kan Yoo et al.   JOURNAL OF CELL BIOLOGY

Lipid raft-dependent activation of dual oxidase 1/H2O2/NF-κB pathway in bronchial epithelial cells

(2011) Lifen Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Dual Oxidase 2 is Essential for the Toll-Like Receptor 5-Mediated Inflammatory Response in Airway Mucosa

(2011) Jung-Hee Joo et al.   ANTIOXIDANTS & REDOX SIGNALING

Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptor

(2011) Ethan R. Block et al.   CELLULAR SIGNALLING

Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides

(2011) Sue Goo Rhee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo

(2011) Sa Kan Yoo et al.   NATURE

Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity

(2011) Candice E Paulsen et al.   Nature Chemical Biology

Feedback regulation of EGFR signalling: decision making by early and delayed loops

(2011) Roi Avraham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

EGF Receptor Exposed to Oxidative Stress Acquires Abnormal Phosphorylation and Aberrant Activated Conformation That Impairs Canonical Dimerization

(2011) Simone Filosto et al.   PLoS One

Remodeling of Purinergic Receptor-Mediated Ca2+ Signaling as a Consequence of EGF-Induced Epithelial-Mesenchymal Transition in Breast Cancer Cells

(2011) Felicity M. Davis et al.   PLoS One

The Role of Purinergic Signaling on Deformation Induced Injury and Repair Responses of Alveolar Epithelial Cells

(2011) Hewan A. Belete et al.   PLoS One

Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide

(2011) D. E. Fomenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADAM17: a molecular switch to control inflammation and tissue regeneration

(2011) Jürgen Scheller et al.   TRENDS IN IMMUNOLOGY

Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila

(2011) Michelle T. Juarez et al.   PLoS Genetics

Ce-Duox1/BLI-3 Generated Reactive Oxygen Species Trigger Protective SKN-1 Activity via p38 MAPK Signaling during Infection in C. elegans

(2011) Ransome van der Hoeven et al.   PLoS Pathogens

The P2Y2 receptor mediates the epithelial injury response and cell migration

(2010) Ilene Boucher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium

(2010) Angela Lee Linderholm et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Thiol isomerases negatively regulate the cellular shedding activity of ADAM17

(2010) Sofie H. Willems et al.   BIOCHEMICAL JOURNAL

ADAM-17: the enzyme that does it all

(2010) Monika Gooz   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Src redox regulation: Again in the front line

(2010) Elisa Giannoni et al.   FREE RADICAL BIOLOGY AND MEDICINE

P2Y2Nucleotide Receptors Mediate Metalloprotease-dependent Phosphorylation of Epidermal Growth Factor Receptor and ErbB3 in Human Salivary Gland Cells

(2010) Ann M. Ratchford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Double-Stranded RNA Induces Shedding of the 34-kDa Soluble TNFR1 from Human Airway Epithelial Cells via TLR3-TRIF-RIP1-Dependent Signaling: Roles for Dual Oxidase 2- and Caspase-Dependent Pathways

(2010) M. Yu et al.   JOURNAL OF IMMUNOLOGY

P2Y2 Nucleotide Receptor-Mediated Responses in Brain Cells

(2010) Troy S. Peterson et al.   MOLECULAR NEUROBIOLOGY

A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17

(2010) T Maretzky et al.   ONCOGENE

Dual oxidase in mucosal immunity and host–microbe homeostasis

(2010) Yun Soo Bae et al.   TRENDS IN IMMUNOLOGY

Visualization of Src Activity at Different Compartments of the Plasma Membrane by FRET Imaging

(2009) Jihye Seong et al.   CHEMISTRY & BIOLOGY

Purinergic receptors in airway epithelia

(2009) Eduardo R Lazarowski et al.   CURRENT OPINION IN PHARMACOLOGY

Oxidative epithelial host defense is regulated by infectious and inflammatory stimuli

(2009) Monica Valencia Gattas et al.   FREE RADICAL BIOLOGY AND MEDICINE

ATP-mediated Activation of the NADPH Oxidase DUOX1 Mediates Airway Epithelial Responses to Bacterial Stimuli

(2009) Agnes W. Boots et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UTP Controls Cell Surface Distribution and Vasomotor Activity of the Human P2Y2Receptor through an Epidermal Growth Factor Receptor-transregulated Mechanism

(2009) Andrés Norambuena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases

(2009) Marcus Gutscher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells

(2009) S. Luxen et al.   JOURNAL OF CELL SCIENCE

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

(2009) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Reactive Oxygen Species Mediate GPCR–induced TACE/ADAM17-dependent Transforming Growth Factor-α Shedding

(2009) Timothy J. Myers et al.   MOLECULAR BIOLOGY OF THE CELL

Direct and specific inactivation of protein tyrosine kinases in the Src and FGFR families by reversible cysteine oxidation

(2009) D. J. Kemble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

(2008) Jonathan L. Koff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Nitric Oxide Regulation of MMP-9 Activation and Its Relationship to Modifications of the Cysteine Switch†

(2008) Sean M. McCarthy et al.   BIOCHEMISTRY

The cysteine-cluster motif of c-Src: Its role for the heavy metal-mediated activation of kinase

(2008) Takeshi Senga et al.   CANCER SCIENCE

c-Src trafficking and co-localization with the EGF receptor promotes EGF ligand-independent EGF receptor activation and signaling

(2008) Mrudula Donepudi et al.   CELLULAR SIGNALLING

Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases

(2008) P-R. Burgel et al.   EUROPEAN RESPIRATORY JOURNAL

Regulation of ROS signal transduction by NADPH oxidase 4 localization

(2008) Kai Chen et al.   JOURNAL OF CELL BIOLOGY

Regulated Airway Goblet Cell Mucin Secretion

(2007) C. William Davis et al.   Annual Review of Physiology

NADPH oxidases in lung biology and pathology: Host defense enzymes, and more

(2007) Albert van der Vliet   FREE RADICAL BIOLOGY AND MEDICINE