Telomerase Reverse Transcriptase Synergizes with Calorie Restriction to Increase Health Span and Extend Mouse Longevity

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

(2012) Bruno Bernardes de Jesus et al.   EMBO Molecular Medicine

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

(2012) Julie A. Mattison et al.   NATURE

The Rate of Increase of Short Telomeres Predicts Longevity in Mammals

(2012) Elsa Vera et al.   Cell Reports

CKIα ablation highlights a critical role for p53 in invasiveness control

(2011) Ela Elyada et al.   NATURE

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

The impact of acute caloric restriction on the metabolic phenotype in male C57BL/6 and DBA/2 mice

(2010) Sarah Hempenstall et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Calorie restriction and cancer prevention: metabolic and molecular mechanisms

(2010) Valter D. Longo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Caloric restriction: From soup to nuts

(2009) Stephen R. Spindler   AGEING RESEARCH REVIEWS

Delayed kinetics of DNA double-strand break processing in normal and pathological aging

(2009) Olga A. Sedelnikova et al.   AGING CELL

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

(2009) Chen-Yu Liao et al.   AGING CELL

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

(2009) P. Martinez et al.   GENES & DEVELOPMENT

Telomere Diseases

(2009) Rodrigo T. Calado et al.   NEW ENGLAND JOURNAL OF MEDICINE

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Caloric restriction, SIRT1 and longevity

(2009) Carles Cantó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice

(2008) Antonia Tomás-Loba et al.   CELL

Caloric Restriction Decreases Cortical Bone Mass but Spares Trabecular Bone in the Mouse Skeleton: Implications for the Regulation of Bone Mass by Body Weight

(2008) Mark W Hamrick et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Caloric Restriction and Aging: Studies in Mice and Monkeys

(2008) Rozalyn M. Anderson et al.   TOXICOLOGIC PATHOLOGY