α-Lipoic Acid Reduces Infarct Size and Preserves Cardiac Function in Rat Myocardial Ischemia/Reperfusion Injury through Activation of PI3K/Akt/Nrf2 Pathway

Lipoic acid – biological activity and therapeutic potential

(2014) Anna Gorąca et al.   Pharmacological Reports

Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response

(2012) Kate Petersen Shay et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

(2012) Houman Ashrafian et al.   Cell Metabolism

α-Lipoic Acid Prevents the Induction of iNOS Gene Expression Through Destabilization of Its mRNA in Proinflammatory Cytokine-Stimulated Hepatocytes

(2012) Masanori Yamada et al.   DIGESTIVE DISEASES AND SCIENCES

Alpha lipoic acid protects heart against myocardial ischemia–reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation

(2012) Lan He et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nrf2-dependent Induction of Proteasome and Pa28αβ Regulator Are Required for Adaptation to Oxidative Stress

(2012) Andrew M. Pickering et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Variation of NDRG2 and c-Myc expression in rat heart during the acute stage of ischemia/reperfusion injury

(2010) Zhongchan Sun et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Inflammation and apoptosis in aortic tissues of aged type II diabetes: Amelioration with α-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism

(2010) Milad S. Bitar et al.   LIFE SCIENCES

U50,488H postconditioning reduces apoptosis after myocardial ischemia and reperfusion

(2010) Guang Tong et al.   LIFE SCIENCES

Anti-Oxidative Effect of Lipoic Acid in Spinal Cord Ischemia/Reperfusion

(2010) Sheyda Shaafi et al.   MEDICAL PRINCIPLES AND PRACTICE

Cellular mechanisms by which lipoic acid confers protection during the early stages of cerebral ischemia: A possible role for calcium

(2010) Marc J.P. Richard et al.   NEUROSCIENCE RESEARCH

Antioxidant Properties of an Endogenous Thiol: Alpha-lipoic Acid, Useful in the Prevention of Cardiovascular Diseases

(2009) Stéliana Ghibu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

(2009) Jiyoung Kim et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Cardioprotective Effects of Alpha-Lipoic Acid on Myocardial Reperfusion Injury: Suppression of Reactive Oxygen Species Generation and Activation of Mitogen-Activated Protein Kinase

(2009) Seok Kyu Oh et al.   Korean Circulation Journal

(−)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells

(2008) Hye-Kyung Na et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The role of lipoic acid in prevention of nitroglycerin tolerance

(2008) Magdalena Dudek et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

(2008) Patrick L. Apopa et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA