Inhibition of Both Protease and Helicase Activities of Hepatitis C Virus NS3 by an Ethyl Acetate Extract of Marine Sponge Amphimedon sp

Antiviral strategies in hepatitis C virus infection

(2012) Christoph Sarrazin et al.   JOURNAL OF HEPATOLOGY

Severe cutaneous eruptions on telaprevir

(2012) Steven T. Chen et al.   JOURNAL OF HEPATOLOGY

Inhibition of Hepatitis C Virus NS3 Helicase by Manoalide

(2012) Kazi Abdus Salam et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of Hepatitis C Virus Replication and Viral Helicase by Ethyl Acetate Extract of the Marine Feather Star Alloeocomatella polycladia

(2012) Atsuya Yamashita et al.   Marine Drugs

Soft Coral Sarcophyton (Cnidaria: Anthozoa: Octocorallia) Species Diversity and Chemotypes

(2012) Satoe Aratake et al.   PLoS One

Exploitation of Lipid Components by Viral and Host Proteins for Hepatitis C Virus Infection

(2012) Kohji Moriishi et al.   Frontiers in Microbiology

The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry

(2011) Sandra Ciesek et al.   HEPATOLOGY

Discovery and development of telaprevir: an NS3-4A protease inhibitor for treating genotype 1 chronic hepatitis C virus

(2011) Ann D Kwong et al.   NATURE BIOTECHNOLOGY

Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection

(2011) Ira M. Jacobson et al.   NEW ENGLAND JOURNAL OF MEDICINE

A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target

(2011) N. Schiering et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review article: specifically targeted anti-viral therapy for hepatitis C - a new era in therapy

(2010) C. M. Lange et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Induced-Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target

(2010) Maxwell D. Cummings et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism and Specificity of a Symmetrical Benzimidazolephenylcarboxamide Helicase Inhibitor

(2010) Craig A. Belon et al.   BIOCHEMISTRY

Multiple effects of silymarin on the hepatitis C virus lifecycle

(2010) Jessica Wagoner et al.   HEPATOLOGY

Involvement of PA28γ in the propagation of hepatitis C virus

(2010) Kohji Moriishi et al.   HEPATOLOGY

Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding

(2010) K. P. Romano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The odyssey of marine pharmaceuticals: a current pipeline perspective

(2010) Alejandro M.S. Mayer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

High-throughput screening assay of hepatitis C virus helicase inhibitors using fluorescence-quenching phenomenon

(2009) Hidenori Tani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Silibinin and Related Compounds Are Direct Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase

(2009) Abdelhakim Ahmed–Belkacem et al.   GASTROENTEROLOGY

Viral resistance to specifically targeted antiviral therapies for hepatitis C (STAT-Cs)

(2009) T. L. Kieffer et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Proanthocyanidin from Blueberry Leaves Suppresses Expression of Subgenomic Hepatitis C Virus RNA

(2009) Masahiko Takeshita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells

(2009) Yuki Nishimura-Sakurai et al.   JOURNAL OF GASTROENTEROLOGY

Antiviral resistance and specifically targeted therapy for HCV (STAT-C)

(2009) A. J. V. Thompson et al.   JOURNAL OF VIRAL HEPATITIS

Telaprevir with Peginterferon and Ribavirin for Chronic HCV Genotype 1 Infection

(2009) John G. McHutchison et al.   NEW ENGLAND JOURNAL OF MEDICINE

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

(2009) J. W.-H. Li et al.   SCIENCE

Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

(2008) F. George Njoroge et al.   ACCOUNTS OF CHEMICAL RESEARCH

Epidemiology of HCV Infection

(2008) V. Baldo et al.   CURRENT PHARMACEUTICAL DESIGN

Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 Helicase

(2008) Rudolf K. F. Beran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drug development from marine natural products

(2008) Tadeusz F. Molinski et al.   NATURE REVIEWS DRUG DISCOVERY