Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies
出版年份 2012 全文链接
标题
Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies
作者
关键词
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出版物
PLoS One
Volume 7, Issue 12, Pages e50920
出版商
Public Library of Science (PLoS)
发表日期
2012-12-28
DOI
10.1371/journal.pone.0050920
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Phase I First-in-Human Study of TRC105 (Anti-Endoglin Antibody) in Patients with Advanced Cancer
- (2012) L. S. Rosen et al. CLINICAL CANCER RESEARCH
- Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting
- (2012) Laurens A. van Meeteren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural and Functional Insights into Endoglin Ligand Recognition and Binding
- (2012) Aaron Alt et al. PLoS One
- BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain
- (2011) Marie Bidart et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- TGF-β Receptor Signaling Pathways in Angiogenesis; Emerging Targets for Anti-Angiogenesis Therapy
- (2011) Laurens A. van Meeteren et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth
- (2011) Roselyne Castonguay et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts
- (2011) Erin Morris et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The physiological role of endoglin in the cardiovascular system
- (2010) José M. López-Novoa et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis
- (2010) Sara I. Cunha et al. JOURNAL OF EXPERIMENTAL MEDICINE
- ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth
- (2010) D. Mitchell et al. MOLECULAR CANCER THERAPEUTICS
- Signaling by members of the TGF-β family in vascular morphogenesis and disease
- (2010) Evangelia Pardali et al. TRENDS IN CELL BIOLOGY
- Endoglin-Targeted Cancer Therapy
- (2010) Ben K. Seon et al. Current Drug Delivery
- The emerging role of TGF-β superfamily coreceptors in cancer
- (2009) Carmelo Bernabeu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells
- (2009) E. S. Shao et al. BLOOD
- Emerging role of bone morphogenetic proteins in angiogenesis
- (2009) Laurent David et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Transforming Growth Factor β Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors
- (2009) Katharine H. Wrighton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bone Morphogenetic Protein (BMP) and Activin Type II Receptors Balance BMP9 Signals Mediated by Activin Receptor-like Kinase-1 in Human Pulmonary Artery Endothelial Cells
- (2009) Paul D. Upton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mural Cell Associated VEGF Is Required for Organotypic Vessel Formation
- (2009) Lasse Evensen et al. PLoS One
- HHT is not a TGF disease
- (2008) S. Bailly BLOOD
- Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor
- (2008) Laurent David et al. CIRCULATION RESEARCH
- Endoglin (CD105): A Marker of Tumor Vasculature and Potential Target for Therapy
- (2008) N. A. Dallas et al. CLINICAL CANCER RESEARCH
- TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch
- (2008) Irwin M Liu et al. EMBO JOURNAL
- Anti-tumor activity of an anti-endoglin monoclonal antibody is enhanced in immunocompetent mice
- (2008) Masanori Tsujie et al. INTERNATIONAL JOURNAL OF CANCER
- Transforming Growth Factor -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth
- (2008) A. C. Daly et al. MOLECULAR AND CELLULAR BIOLOGY
- Endoglin-Mediated Vascular Remodeling: Mechanisms Underlying Hereditary Hemorrhagic Telangiectasia
- (2008) Franck Lebrin et al. TRENDS IN CARDIOVASCULAR MEDICINE
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