Hyperlipidemia and Atherosclerotic Lesion Development in Ldlr-Deficient Mice on a Long-Term High-Fat Diet

Inhibition of Lipoprotein-Associated Phospholipase A2 Ameliorates Inflammation and Decreases Atherosclerotic Plaque Formation in ApoE-Deficient Mice

(2011) Wen-yi Wang et al.   PLoS One

Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation

(2010) George S. Abela   Journal of Clinical Lipidology

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Effect of Cholesterol Crystals on Plaques and Intima in Arteries of Patients With Acute Coronary and Cerebrovascular Syndromes

(2009) George S. Abela et al.   AMERICAN JOURNAL OF CARDIOLOGY

Differential anti-atherosclerotic effects in the innominate artery and aortic sinus by the liver X receptor agonist T0901317

(2008) Dacheng Peng et al.   ATHEROSCLEROSIS

Physical factors that trigger cholesterol crystallization leading to plaque rupture

(2008) Ameeth Vedre et al.   ATHEROSCLEROSIS

Translating molecular discoveries into new therapies for atherosclerosis

(2008) Daniel J. Rader et al.   NATURE