BIM-Mediated AKT Phosphorylation Is a Key Modulator of Arsenic Trioxide-Induced Apoptosis in Cisplatin-Sensitive and -Resistant Ovarian Cancer Cells

Induction of B-Chronic Lymphocytic Leukemia Cell Apoptosis by Arsenic Trioxide Involves Suppression of the Phosphoinositide 3-Kinase/Akt Survival Pathway via c-jun-NH2 Terminal Kinase Activation and PTEN Upregulation

(2010) J. Redondo-Munoz et al.   CLINICAL CANCER RESEARCH

Inhibitors of the Ubiquitin-Proteasome System and the Cell Death Machinery: How Many Pathways are Activated?

(2010) Claudio Brancolini   Current Molecular Pharmacology

TORC-Specific Phosphorylation of Mammalian Target of Rapamycin (mTOR): Phospho-Ser2481 Is a Marker for Intact mTOR Signaling Complex 2

(2009) J. Copp et al.   CANCER RESEARCH

Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: Therapeutic potential for ovarian cancer

(2009) Ning Zhang et al.   CANCER SCIENCE

Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells

(2009) K. Simonin et al.   MOLECULAR CANCER THERAPEUTICS

Enhancing the efficacy of cisplatin in ovarian cancer treatment – could arsenic have a role

(2009) C William Helm et al.   Journal of Ovarian Research

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma

(2008) A. A. Morales et al.   BLOOD

Down-regulation of Phospho-Akt Is a Major Molecular Determinant of Bortezomib-Induced Apoptosis in Hepatocellular Carcinoma Cells

(2008) K.-F. Chen et al.   CANCER RESEARCH

Cysteine 62 of Bax Is Critical for Its Conformational Activation and Its Proapoptotic Activity in Response to H2O2-induced Apoptosis

(2008) Chunlai Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arsenic trioxide decreases AKT protein in a caspase-dependent manner

(2008) Koren K. Mann et al.   MOLECULAR CANCER THERAPEUTICS