Suppression of STAT3 and HIF-1 Alpha Mediates Anti-Angiogenic Activity of Betulinic Acid in Hypoxic PC-3 Prostate Cancer Cells
出版年份 2011 全文链接
标题
Suppression of STAT3 and HIF-1 Alpha Mediates Anti-Angiogenic Activity of Betulinic Acid in Hypoxic PC-3 Prostate Cancer Cells
作者
关键词
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出版物
PLoS One
Volume 6, Issue 6, Pages e21492
出版商
Public Library of Science (PLoS)
发表日期
2011-06-25
DOI
10.1371/journal.pone.0021492
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- (2009) A. Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
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- HIF-1 regulation: not so easy come, easy go
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