Edaravone Guards Dopamine Neurons in a Rotenone Model for Parkinson's Disease

Long-Term Efficacy and Safety of Human Umbilical Cord Mesenchymal Stromal Cells in Rotenone-Induced Hemiparkinsonian Rats

(2010) Nian Xiong et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life

(2010) Zhicheng Lin et al.   FASEB JOURNAL

VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson’s disease

(2010) N Xiong et al.   GENE THERAPY

In Vivo Measurement of Vesicular Monoamine Transporter Type 2 Density in Parkinson Disease with 18F-AV-133

(2010) N. Okamura et al.   JOURNAL OF NUCLEAR MEDICINE

Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease

(2009) Sung Tae Kim et al.   BRAIN RESEARCH

WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease

(2009) David A. Price et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism

(2009) Corinne Beurrier et al.   FASEB JOURNAL

The scientific and clinical basis for the treatment of Parkinson disease (2009)

(2009) C. W. Olanow et al.   NEUROLOGY

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

(2009) Eugene V. Mosharov et al.   NEURON

EFFECT OF A FREE RADICAL SCAVENGER, EDARAVONE, IN THE TREATMENT OF PATIENTS WITH ANEURYSMAL SUBARACHNOID HEMORRHAGE

(2009) Akira Munakata et al.   NEUROSURGERY

The Novel Free Radical Scavenger, Edaravone, Increases Neural Stem Cell Number Around the Area of Damage Following Rat Traumatic Brain Injury

(2009) Tatsuki Itoh et al.   NEUROTOXICITY RESEARCH

Stereotaxical Infusion of Rotenone: A Reliable Rodent Model for Parkinson's Disease

(2009) Nian Xiong et al.   PLoS One

Oxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells

(2009) Shichang Liu et al.   TOXICOLOGY

Effects of glutamate and α2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats

(2009) Mesbah Alam et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons

(2008) Wen Ji Yuan et al.   BMC NEUROSCIENCE

Evidence that oxidative stress is linked to anxiety-related behaviour in mice

(2008) Hassan Rammal et al.   BRAIN BEHAVIOR AND IMMUNITY

Treatment with edaravone, initiated at symptom onset, slows motor decline and decreases SOD1 deposition in ALS mice

(2008) Hidefumi Ito et al.   EXPERIMENTAL NEUROLOGY

Edaravone protects against MPP+-induced cytotoxicity in rat primary cultured astrocytes via inhibition of mitochondrial apoptotic pathway

(2008) Hui Chen et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial Complex I Inhibitor Rotenone Inhibits and Redistributes Vesicular Monoamine Transporter 2 via Nitration in Human Dopaminergic SH-SY5Y Cells

(2008) M. Watabe et al.   MOLECULAR PHARMACOLOGY

Edaravone, a Free Radical Scavenger, Inhibits MMP-9–Related Brain Hemorrhage in Rats Treated With Tissue Plasminogen Activator

(2008) Kenji Yagi et al.   STROKE

The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?

(2008) Hirokazu Fukui et al.   TRENDS IN NEUROSCIENCES

Edaravone Attenuates Brain Edema and Neurologic Deficits in a Rat Model of Acute Intracerebral Hemorrhage

(2007) Takehiro Nakamura et al.   STROKE