High-mobility group box 1 protein and its role in severe acute pancreatitis

HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity

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Targeting HMGB1 in the treatment of sepsis

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High-mobility group box-1 and its role in angiogenesis

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Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti–high mobility group box 1 activity: targeting of colon cancer

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Anti-HMGB1 Neutralizing Antibody Ameliorates Neutrophilic Airway Inflammation by Suppressing Dendritic Cell-Mediated Th17 Polarization

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Expression and significance of HMGB1, TLR4 and NF-κB p65 in human epidermal tumors

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Ethyl pyruvate significantly inhibits tumour necrosis factor-α, interleukin-1β and high mobility group box 1 releasing and attenuates sodium taurocholate-induced severe acute pancreatitis associated with acute lung injury

(2013) Z.-G. Luan et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Intracellular Hmgb1 Inhibits Inflammatory Nucleosome Release and Limits Acute Pancreatitis in Mice

(2013) Rui Kang et al.   GASTROENTEROLOGY

Downregulation of HMGB1 protects against the development of acute lung injury after severe acute pancreatitis

(2013) Zheng-Gang Luan et al.   IMMUNOBIOLOGY

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

Scolopendra subspinipes mutilansprotected the cerulein-induced acute pancreatitis by inhibiting high-mobility group box protein-1

(2013) Il-Joo Jo   WORLD JOURNAL OF GASTROENTEROLOGY

Age-dependent vulnerability to experimental acute pancreatitis is associated with increased systemic inflammation and thrombosis

(2012) Daiki Okamura et al.   AGING CELL

Autophagy and pancreatitis

(2012) Anna S. Gukovskaya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Determinant-Based Classification of Acute Pancreatitis Severity

(2012) E. Patchen Dellinger et al.   ANNALS OF SURGERY

Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus

(2012) Peter A Banks et al.   GUT

Impaired autophagy and organellar dysfunction in pancreatitis

(2012) Ilya Gukovsky et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Protective effect of ethyl pyruvate on pancreas injury in rats with severe acute pancreatitis

(2012) Zheng-Gang Luan et al.   JOURNAL OF SURGICAL RESEARCH

Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1

(2012) J R van Beijnum et al.   ONCOGENE

Therapeutic Treatment With Ethyl Pyruvate Attenuates the Severity of Liver Injury in Rats With Severe Acute Pancreatitis

(2012) Zheng-Gang Luan et al.   PANCREAS

Severe sepsis and systemic inflammatory response syndrome in emergency department patients with suspected severe infection

(2012) Patrik Gille-Johnson et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Calcium and Reactive Oxygen Species in Acute Pancreatitis: Friend or Foe?

(2011) David M. Booth et al.   ANTIOXIDANTS & REDOX SIGNALING

The Role of Nitric Oxide in the Physiology and Pathophysiology of the Exocrine Pancreas

(2011) Péter Hegyi et al.   ANTIOXIDANTS & REDOX SIGNALING

The effect of HMGB1 A box on lung injury in mice with acute pancreatitis

(2011) Xiangqian Kong et al.   BIOFACTORS

Molecular mechanisms of pancreatic injury

(2011) Raghuwansh P. Sah et al.   CURRENT OPINION IN GASTROENTEROLOGY

Redox signaling and histone acetylation in acute pancreatitis

(2011) Javier Escobar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cytokines and Organ Failure in Acute Pancreatitis

(2011) Marie Louise Malmstrøm et al.   PANCREAS

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

The release of high mobility group box 1 in apoptosis is triggered by nucleosomal DNA fragmentation

(2010) Yoichiro Yamada et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

HMGB1, a potent proinflammatory cytokine in sepsis

(2010) Wenchang Huang et al.   CYTOKINE

Zymophagy, a Novel Selective Autophagy Pathway Mediated by VMP1-USP9x-p62, Prevents Pancreatic Cell Death

(2010) Daniel Grasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Role of High-Mobility Group Box 1 Protein in the Pathogenesis of Intestinal Barrier Injury in Rats With Severe Acute Pancreatitis

(2010) Zheng-Gang Luan et al.   PANCREAS

Effect of Polymyxin B-Immobilized Fiber Hemoperfusion on Serum High Mobility Group Box-1 Protein Levels and Oxidative Stress in Patients With Acute Respiratory Distress Syndrome

(2009) Tsukasa Nakamura et al.   ASAIO JOURNAL

Targeting HMGB1 in inflammation

(2009) Huan Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Ethyl pyruvate

(2009) Mitchell P Fink   Current Opinion in Anesthesiology

Antioxidant Inhibits HMGB1 Expression and Reduces Pancreas Injury in Rats with Severe Acute Pancreatitis

(2009) Zhong Wei Zhang et al.   DIGESTIVE DISEASES AND SCIENCES

Protective Effect of HMGB1 A Box on Organ Injury of Acute Pancreatitis in Mice

(2009) Hai Yuan et al.   PANCREAS

Circulating Levels of a Soluble Form of Receptor for Advanced Glycation End Products and High-Mobility Group Box Chromosomal Protein 1 in Patients With Acute Pancreatitis

(2009) Outi Lindström et al.   PANCREAS

Plasma Concentrations of High-Mobility Group Box Protein 1, Soluble Receptor for Advanced Glycation End-Products and Circulating DNA in Patients with Acute Pancreatitis

(2009) Á.K. Kocsis et al.   PANCREATOLOGY

Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)

(2008) Judy R. van Beijnum et al.   ANGIOGENESIS

Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling

(2008) T. Kohno et al.   CARDIOVASCULAR RESEARCH

Ethyl Pyruvate Ameliorates Liver Injury Secondary to Severe Acute Pancreatitis

(2008) Runkuan Yang et al.   JOURNAL OF SURGICAL RESEARCH

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(2008) John Klune et al.   MOLECULAR MEDICINE