A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis
出版年份 2015 全文链接
标题
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis
作者
关键词
3D culture, Neurotoxicity, Resilience, microRNA, Rotenone
出版物
ARCHIVES OF TOXICOLOGY
Volume 90, Issue 11, Pages 2725-2743
出版商
Springer Nature
发表日期
2015-12-09
DOI
10.1007/s00204-015-1637-z
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Food for thought … on the evolution of toxicology and the phasing out of animal testing
- (2016) Thomas Hartung ALTEX-Alternatives to Animal Experimentation
- From smoking guns to footprints: mining for critical events of toxicity pathways in transcriptome data
- (2015) Jörg Rahnenführer et al. ARCHIVES OF TOXICOLOGY
- MPTP’s Pathway of Toxicity Indicates Central Role of Transcription Factor SP1
- (2015) Alexandra Maertens et al. ARCHIVES OF TOXICOLOGY
- Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolism
- (2015) Liudmila Efremova et al. BRITISH JOURNAL OF PHARMACOLOGY
- 6-OHDA-Induced Changes in Parkinson`s Disease-Related Gene Expression are not Affected by the Overexpression of PGAM5 in In Vitro Differentiated Embryonic Mesencephalic Cells
- (2015) Tomasz Maciej Stępkowski et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- LRRK2 mutations and neurotoxicant susceptibility
- (2015) Jang-Won Lee et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Derivation, Expansion, and Motor Neuron Differentiation of Human-Induced Pluripotent Stem Cells with Non-Integrating Episomal Vectors and a Defined Xenogeneic-free Culture System
- (2015) Wentao Hu et al. MOLECULAR NEUROBIOLOGY
- The Parkinson Disease Mitochondrial Hypothesis
- (2015) Sandra Franco-Iborra et al. NEUROSCIENTIST
- Comprehensive Assessment of Genetic Sequence Variants in the Antioxidant ‘Master Regulator’ Nrf2 in Idiopathic Parkinson’s Disease
- (2015) Michael Todorovic et al. PLoS One
- Modeling Chemotherapeutic Neurotoxicity with Human Induced Pluripotent Stem Cell-Derived Neuronal Cells
- (2015) Heather E. Wheeler et al. PLoS One
- Cellular resilience
- (2015) Lena Smirnova ALTEX-Alternatives to Animal Experimentation
- Cell-based assays for Parkinson's disease using differentiated human LUHMES cells
- (2014) Xiao-min Zhang et al. ACTA PHARMACOLOGICA SINICA
- 3D — A new dimension of in vitro research
- (2014) Thomas Hartung ADVANCED DRUG DELIVERY REVIEWS
- Stem Cells on the Brain: Modeling Neurodevelopmental and Neurodegenerative Diseases Using Human Induced Pluripotent Stem Cells
- (2014) Priya Srikanth et al. JOURNAL OF NEUROGENETICS
- MicroRNA-7 Protects against 1-Methyl-4-Phenylpyridinium-Induced Cell Death by Targeting RelA
- (2014) D. C. Choi et al. JOURNAL OF NEUROSCIENCE
- MicroRNA Profiling as Tool for In Vitro Developmental Neurotoxicity Testing: The Case of Sodium Valproate
- (2014) Lena Smirnova et al. PLoS One
- Studying neurodegenerative diseases in culture models
- (2014) Johannes C.M. Schlachetzki et al. REVISTA BRASILEIRA DE PSIQUIATRIA
- miR-7 and miR-153 protect neurons against MPP+-induced cell death via upregulation of mTOR pathway
- (2014) Apostolia Fragkouli et al. Frontiers in Cellular Neuroscience
- Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+
- (2014) A K Krug et al. Cell Death & Disease
- Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases
- (2014) Stefan Schildknecht ALTEX-Alternatives to Animal Experimentation
- Consensus report on the future of animal-free systemic toxicity testing
- (2014) Marcel Leist ALTEX-Alternatives to Animal Experimentation
- Current approaches and future role of high content imaging in safety sciences and drug discovery
- (2014) Erwin van Vliet ALTEX-Alternatives to Animal Experimentation
- State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology
- (2014) Natalie Alépée ALTEX-Alternatives to Animal Experimentation
- Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants
- (2013) Anne K. Krug et al. ARCHIVES OF TOXICOLOGY
- Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice
- (2013) Marcel Leist et al. ARCHIVES OF TOXICOLOGY
- Monocrotophos in Gandaman village: India school lunch deaths and need for improved toxicity testing
- (2013) Karl-Heinz Krause et al. ARCHIVES OF TOXICOLOGY
- miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing
- (2013) Giorgia Pallocca et al. CELL BIOLOGY AND TOXICOLOGY
- MitomiRs delineating the intracellular localization of microRNAs at mitochondria
- (2013) S. Bandiera et al. FREE RADICAL BIOLOGY AND MEDICINE
- Integrating Pathways of Parkinson's Disease in a Molecular Interaction Map
- (2013) Kazuhiro A. Fujita et al. MOLECULAR NEUROBIOLOGY
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities
- (2013) Navneet Ammal Kaidery et al. Neurotherapeutics
- Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2
- (2013) J H Kim et al. Cell Death & Disease
- Toward a 3D model of human brain development for studying gene/environment interactions
- (2013) Helena T Hogberg et al. Stem Cell Research & Therapy
- miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression
- (2012) D. Yang et al. JOURNAL OF CELL SCIENCE
- MicroRNAs in Parkinson's disease
- (2012) M. Maral Mouradian NEUROBIOLOGY OF DISEASE
- Non-coding RNAs—Novel targets in neurotoxicity
- (2012) Tamara L. Tal et al. NEUROTOXICOLOGY
- Highlight report: towards the replacement of in vivo repeated dose systemic toxicity testing
- (2011) Jan G. Hengstler et al. ARCHIVES OF TOXICOLOGY
- Rotenone, Paraquat, and Parkinson’s Disease
- (2011) Caroline M. Tanner et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Parkinson’s disease risk from ambient exposure to pesticides
- (2011) Anthony Wang et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Control of mitochondrial activity by miRNAs
- (2011) Peifeng Li et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line
- (2011) Diana Scholz et al. JOURNAL OF NEUROCHEMISTRY
- miR-210: The Master Hypoxamir
- (2011) YUK C. CHAN et al. MICROCIRCULATION
- Dopamine-Regulated MicroRNA MiR-181a Controls GluA2 Surface Expression in Hippocampal Neurons
- (2011) R. Saba et al. MOLECULAR AND CELLULAR BIOLOGY
- Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain
- (2011) Hiroshi Hama et al. NATURE NEUROSCIENCE
- Assessment of Chemical-Induced Impairment of Human Neurite Outgrowth by Multiparametric Live Cell Imaging in High-Density Cultures
- (2011) Nina V. Stiegler et al. TOXICOLOGICAL SCIENCES
- MicroRNAs: Master Regulators of Ethanol Abuse and Toxicity?
- (2010) Rajesh C. Miranda et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Roles of small regulatory RNAs in determining neuronal identity
- (2010) Xuekun Li et al. NATURE REVIEWS NEUROSCIENCE
- Dysregulated microRNAs in neurodegenerative disorders
- (2010) Pierre Lau et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Wnt1-cre-mediated Conditional Loss of Dicer Results in Malformation of the Midbrain and Cerebellum and Failure of Neural Crest and Dopaminergic Differentiation in Mice
- (2010) Tianwen Huang et al. Journal of Molecular Cell Biology
- Parkinson's Disease and Residential Exposure to Maneb and Paraquat From Agricultural Applications in the Central Valley of California
- (2009) S. Costello et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Extracellular matrix in plasticity and epileptogenesis
- (2009) Alexander Dityatev et al. Neuron Glia Biology
- Repression of -synuclein expression and toxicity by microRNA-7
- (2009) E. Junn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Paper-supported 3D cell culture for tissue-based bioassays
- (2009) R. Derda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells
- (2009) Stefan Schildknecht et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Nicotine modulates expression of miR-140*, which targets the 3′-untranslated region of dynamin 1 gene (Dnm1)
- (2008) Weihua Huang et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Microtubules in Dendritic Spine Development
- (2008) J. Gu et al. JOURNAL OF NEUROSCIENCE
- Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells
- (2008) M Kathleen Borland et al. Molecular Neurodegeneration
- MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary
- (2008) Christoph Leucht et al. NATURE NEUROSCIENCE
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
- Oxidative and Inflammatory Pathways in Parkinson’s Disease
- (2008) Rebecca L. Miller et al. NEUROCHEMICAL RESEARCH
- Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
- (2008) Claire Henchcliffe et al. Nature clinical practice. Neurology
- A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine
- (2007) Erwin van Vliet et al. NEUROTOXICOLOGY
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