Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities
出版年份 2013 全文链接
标题
Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities
作者
关键词
Parkinson’s disease, Epigenetics, DNA methylation, Histones, MicroRNA
出版物
Neurotherapeutics
Volume 10, Issue 4, Pages 698-708
出版商
Springer Nature
发表日期
2013-09-12
DOI
10.1007/s13311-013-0211-8
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- DNA methylation dynamics in health and disease
- (2013) Yehudit Bergman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson’s disease
- (2013) R. St. Laurent et al. NEUROSCIENCE
- The genetics and neuropathology of Parkinson’s disease
- (2012) Henry Houlden et al. ACTA NEUROPATHOLOGICA
- Occupational exposure to pesticides and Parkinson's disease: A systematic review and meta-analysis of cohort studies
- (2012) Geneviève Van Maele-Fabry et al. ENVIRONMENT INTERNATIONAL
- Effect of valproic acid on mitochondrial epigenetics
- (2012) Hu Chen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson’s disease
- (2012) Almas Siddiqui et al. FREE RADICAL BIOLOGY AND MEDICINE
- MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein
- (2012) Hyun Jin Cho et al. HUMAN MOLECULAR GENETICS
- Genome-wide Epigenetic Data Facilitate Understanding of Disease Susceptibility Association Studies
- (2012) Ross C. Hardison JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration
- (2012) Anumantha Kanthasamy et al. NEUROTOXICOLOGY
- Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease
- (2012) Avik Roy et al. PLoS One
- An Intrinsically Disordered Region of the Acetyltransferase p300 with Similarity to Prion-Like Domains Plays a Role in Aggregation
- (2012) Alexander Kirilyuk et al. PLoS One
- Emerging roles of epigenetic mechanisms in Parkinson’s disease
- (2011) Ehsan Habibi et al. FUNCTIONAL & INTEGRATIVE GENOMICS
- MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
- (2011) Elena Miñones-Moyano et al. HUMAN MOLECULAR GENETICS
- Distinct DNA methylation changes highly correlated with chronological age in the human brain
- (2011) Dena G. Hernandez et al. HUMAN MOLECULAR GENETICS
- Study of Methylation Levels of Parkin Gene Promoter in Parkinson's Disease Patients
- (2011) Miao Cai et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease
- (2011) Wenbo Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein Sequesters Dnmt1 from the Nucleus
- (2011) Paula Desplats et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of blood microRNAs associated to Parkinsońs disease
- (2011) Regina Margis et al. JOURNAL OF BIOTECHNOLOGY
- -Synuclein Negatively Regulates Protein Kinase C Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity
- (2011) H. Jin et al. JOURNAL OF NEUROSCIENCE
- Trichloroethylene and Parkinson Disease
- (2011) Fariha Zaheer et al. NEUROLOGIC CLINICS
- Next-Generation Sequencing Reveals Regional Differences of the α-Synuclein Methylation State Independent of Lewy Body Disease
- (2011) L. de Boni et al. NEUROMOLECULAR MEDICINE
- Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
- (2011) S.K. Kidd et al. NEUROSCIENCE
- Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration
- (2011) C. Song et al. NEUROTOXICOLOGY
- Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
- (2011) Bobby Thomas et al. PLoS One
- A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease
- (2011) et al. PLoS Genetics
- Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition
- (2010) Sarah K. Kidd et al. BRAIN RESEARCH
- Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease
- (2010) Rodrigo Franco et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Allelic imbalance of expression and epigenetic regulation within the alpha-synuclein wild-type and p.Ala53Thr alleles in Parkinson disease
- (2010) Gerassimos E. Voutsinas et al. HUMAN MUTATION
- Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153
- (2010) Epaminondas Doxakis JOURNAL OF BIOLOGICAL CHEMISTRY
- Global microRNA Expression Profiling of Caenorhabditis elegans Parkinson's Disease Models
- (2010) Suvi Asikainen et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Methylation Regulates Alpha-Synuclein Expression and Is Decreased in Parkinson's Disease Patients' Brains
- (2010) A. Jowaed et al. JOURNAL OF NEUROSCIENCE
- Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration
- (2010) C. Song et al. MOLECULAR PHARMACOLOGY
- Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
- (2010) Stephan Gehrke et al. NATURE
- Epigenetic modifications and human disease
- (2010) Anna Portela et al. NATURE BIOTECHNOLOGY
- Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons
- (2010) Zoya Marinova et al. NEUROPHARMACOLOGY
- Potent neuroprotective effects of novel structural derivatives of valproic acid: Potential roles of HDAC inhibition and HSP70 induction
- (2010) Yan Leng et al. NEUROSCIENCE LETTERS
- CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease
- (2010) Lumine Matsumoto et al. PLoS One
- PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
- (2010) B. Zheng et al. Science Translational Medicine
- Genetic Inactivation of Dopamine D1 but Not D2 Receptors Inhibits L-DOPA–Induced Dyskinesia and Histone Activation
- (2009) Sanja Darmopil et al. BIOLOGICAL PSYCHIATRY
- Methylation Status and Neurodegenerative Markers in Parkinson Disease
- (2009) R. Obeid et al. CLINICAL CHEMISTRY
- Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation
- (2009) Zoya Marinova et al. JOURNAL OF NEUROCHEMISTRY
- DNA Methylation of Alzheimer Disease and Tauopathy-Related Genes in Postmortem Brain
- (2009) Marta Barrachina et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Aging-Associated Alteration of Subtelomeric Methylation in Parkinson's Disease
- (2009) T. Maeda et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- α-Synuclein and neuronal cell death
- (2009) Mark R Cookson Molecular Neurodegeneration
- HDAC2 negatively regulates memory formation and synaptic plasticity
- (2009) Ji-Song Guan et al. NATURE
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Nucleosome positioning and gene regulation: advances through genomics
- (2009) Cizhong Jiang et al. NATURE REVIEWS GENETICS
- Urocortin modulates dopaminergic neuronal survival via inhibition of glycogen synthase kinase-3β and histone deacetylase
- (2009) Hsin-Yi Huang et al. NEUROBIOLOGY OF AGING
- Repression of -synuclein expression and toxicity by microRNA-7
- (2009) E. Junn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Variation in the miRNA-433 Binding Site of FGF20 Confers Risk for Parkinson Disease by Overexpression of α-Synuclein
- (2008) Gaofeng Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development
- (2008) Jessica L. MacDonald et al. DEVELOPMENTAL DYNAMICS
- Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
- (2008) Yuzuru Imai et al. EMBO JOURNAL
- Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease
- (2008) Judit Pallos et al. HUMAN MOLECULAR GENETICS
- Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons
- (2008) Xuefei Wu et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Striatal histone modifications in models of levodopa-induced dyskinesia
- (2008) Anthony P. Nicholas et al. JOURNAL OF NEUROCHEMISTRY
- Moving AHEAD with an international human epigenome project
- (2008) et al. NATURE
- MicroRNA and proteome expression profiling in early-symptomatic α-synuclein(A30P)-transgenic mice
- (2008) Frank Gillardon et al. Proteomics Clinical Applications
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