RBPJ inhibition impairs the growth of lung cancer

Blockade of Notch Signaling in Tumor-Bearing Mice May Lead to Tumor Regression, Progression, or Metastasis, Depending on Tumor Cell Types

(2015) Xing-Bin Hu et al.   NEOPLASIA

Rnd3 Regulates Lung Cancer Cell Proliferation through Notch Signaling

(2014) Yongjun Tang et al.   PLoS One

M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7

(2014) Xiangwei Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SEMA4b inhibits MMP9 to prevent metastasis of non-small cell lung cancer

(2014) Hong Jian et al.   TUMOR BIOLOGY

MMP9 activation triggered by epidermal growth factor induced FoxO1 nuclear exclusion in non-small cell lung cancer

(2014) Jun Pei et al.   TUMOR BIOLOGY

Ubiquitin Ligases and Cell Cycle Control

(2013) Leonardo K. Teixeira et al.   Annual Review of Biochemistry

Notch Pathway Activity Identifies Cells with Cancer Stem Cell-like Properties and Correlates with Worse Survival in Lung Adenocarcinoma

(2013) K. A. Hassan et al.   CLINICAL CANCER RESEARCH

Hemogenic Endothelial Cell Specification Requires c-Kit, Notch Signaling, and p27-Mediated Cell-Cycle Control

(2013) Kathrina L. Marcelo et al.   DEVELOPMENTAL CELL

Dynamic binding of RBPJ is determined by Notch signaling status

(2013) D. Castel et al.   GENES & DEVELOPMENT

Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of NSCLC

(2013) A.G. Pallis et al.   LUNG CANCER

Surgery for NSCLC in the era of personalized medicine

(2013) Tetsuya Mitsudomi et al.   Nature Reviews Clinical Oncology

High NOTCH activity induces radiation resistance in non small cell lung cancer

(2013) Jan Theys et al.   RADIOTHERAPY AND ONCOLOGY

Cell cycle control across the eukaryotic kingdom

(2013) Hirofumi Harashima et al.   TRENDS IN CELL BIOLOGY

Therapeutic Effect of γ-Secretase Inhibition in KrasG12V-Driven Non-Small Cell Lung Carcinoma by Derepression of DUSP1 and Inhibition of ERK

(2012) Antonio Maraver et al.   CANCER CELL

Notch pathway is involved in high glucose-induced apoptosis in podocytes via Bcl-2 and p53 pathways

(2012) Feng Gao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

p21 and Notch Signalings in the Persistently Altered Vagina Induced by Neonatal Diethylstilbestrol Exposure in Mice

(2012) Takeshi NAKAMURA et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

RBPJ Is a Novel Target for Rhabdomyosarcoma Therapy

(2012) Hiroko Nagao et al.   PLoS One

SIRT1 Regulates Endothelial Notch Signaling in Lung Cancer

(2012) Mian Xie et al.   PLoS One

Rb inactivation in cell cycle and cancer: The puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase

(2011) Sabine Paternot et al.   CELL CYCLE

Stem cell and lung cancer development: blaming the Wnt, Hh and Notch signalling pathway

(2011) María Rosario García Campelo et al.   Clinical & Translational Oncology

Notch signaling in lung cancer

(2011) Paola Galluzzo et al.   Expert Review of Anticancer Therapy

Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation

(2011) Xiangming Ji et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses

(2010) Yao-Chun Wang et al.   CANCER RESEARCH

Alterations of the Notch pathway in lung cancer

(2009) Britta Westhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling

(2008) K. Hori et al.   GENES & DEVELOPMENT

Notch-1 regulates Akt signaling pathway and the expression of cell cycle regulatory proteins cyclin D1, CDK2 and p21 in T-ALL cell lines

(2008) Dongmei Guo et al.   LEUKEMIA RESEARCH