Ubiquitin Ligases and Cell Cycle Control

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Plk2 regulates centriole duplication through phosphorylation-mediated degradation of Fbxw7 (human Cdc4)

(2012) Onur Cizmecioglu et al.   JOURNAL OF CELL SCIENCE

Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis

(2012) Chi-Kuo Hu et al.   MOLECULAR BIOLOGY OF THE CELL

Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface

(2012) David M. Duda et al.   MOLECULAR CELL

The Glomuvenous Malformation Protein Glomulin Binds Rbx1 and Regulates Cullin RING Ligase-Mediated Turnover of Fbw7

(2012) Adriana E. Tron et al.   MOLECULAR CELL

Structure of the mitotic checkpoint complex

(2012) William C. H. Chao et al.   NATURE

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

(2012) Nevena V. Dimova et al.   NATURE CELL BIOLOGY

Ubiquitination of Cdc20 by the APC Occurs through an Intramolecular Mechanism

(2011) Ian T. Foe et al.   CURRENT BIOLOGY

The F Box Protein Partner of Paired Regulates Stability of Drosophila Centromeric Histone H3, CenH3CID

(2011) Olga Moreno-Moreno et al.   CURRENT BIOLOGY

Regulation of Ubiquitin Chain Initiation to Control the Timing of Substrate Degradation

(2011) Adam Williamson et al.   MOLECULAR CELL

Homeostatic Control of Mitotic Arrest

(2011) Gianluca Varetti et al.   MOLECULAR CELL

Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase

(2011) Mardo Kõivomägi et al.   NATURE

FBXW5 controls centrosome number

(2011) Julia Pagan et al.   NATURE CELL BIOLOGY

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment

(2011) Jörg Mansfeld et al.   NATURE CELL BIOLOGY

The SCF–FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication

(2011) Anja Puklowski et al.   NATURE CELL BIOLOGY

The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

(2011) Allan M. Weissman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chfr and RNF8 synergistically regulate ATM activation

(2011) Jiaxue Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Constructing and decoding unconventional ubiquitin chains

(2011) Christian Behrends et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insights into anaphase-promoting complex function and mechanism

(2011) D. Barford   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quality control in the initiation of eukaryotic DNA replication

(2011) J. F. X. Diffley   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Eukaryotic Chromosome DNA Replication: Where, When, and How?

(2010) Hisao Masai et al.   Annual Review of Biochemistry

APC/C-Cdh1

(2010) Xinxian Qiao et al.   CELL CYCLE

How cyclin A destruction escapes the spindle assembly checkpoint

(2010) Barbara Di Fiore et al.   JOURNAL OF CELL BIOLOGY

The SUMO protease SENP6 is essential for inner kinetochore assembly

(2010) Debaditya Mukhopadhyay et al.   JOURNAL OF CELL BIOLOGY

Regulated Degradation of Spindle Assembly Factors by the Anaphase-Promoting Complex

(2010) Ling Song et al.   MOLECULAR CELL

Psh1 Is an E3 Ubiquitin Ligase that Targets the Centromeric Histone Variant Cse4

(2010) Geetha Hewawasam et al.   MOLECULAR CELL

An E3 Ubiquitin Ligase Prevents Ectopic Localization of the Centromeric Histone H3 Variant via the Centromere Targeting Domain

(2010) Prerana Ranjitkar et al.   MOLECULAR CELL

Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as the D-box co-receptor

(2010) Paula C. A. da Fonseca et al.   NATURE

SCFCyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation

(2010) Vincenzo D’Angiolella et al.   NATURE

Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction

(2010) Y Honaker et al.   ONCOGENE

The ubiquitous nature of cancer: the role of the SCFFbw7 complex in development and transformation

(2010) K M Crusio et al.   ONCOGENE

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Control of cell growth by the SCF and APC/C ubiquitin ligases

(2009) Jeffrey R Skaar et al.   CURRENT OPINION IN CELL BIOLOGY

BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/CCdc20 in Interphase

(2009) Liviu A. Malureanu et al.   DEVELOPMENTAL CELL

Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding

(2009) Anita Kulukian et al.   DEVELOPMENTAL CELL

The SCFSlimbubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication

(2009) Gregory C. Rogers et al.   JOURNAL OF CELL BIOLOGY

The Cul3–KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis

(2009) Sarah Maerki et al.   JOURNAL OF CELL BIOLOGY

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression

(2009) R Wäsch et al.   ONCOGENE

Structure of the Anaphase-Promoting Complex/Cyclosome Interacting with a Mitotic Checkpoint Complex

(2009) F. Herzog et al.   SCIENCE

The Influence of Catalysis on Mad2 Activation Dynamics

(2009) Marco Simonetta et al.   PLOS BIOLOGY

Regulation of APC/C Activators in Mitosis and Meiosis

(2008) Jillian A. Pesin et al.   Annual Review of Cell and Developmental Biology

The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

(2008) J. Guerrero-Santoro et al.   CANCER RESEARCH

The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint

(2008) Florian Bassermann et al.   CELL

Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex

(2008) Lingyan Jin et al.   CELL

The SCF/Slimb Ubiquitin Ligase Limits Centrosome Amplification through Degradation of SAK/PLK4

(2008) Inês Cunha-Ferreira et al.   CURRENT BIOLOGY

Genome-wide analysis reveals a cell cycle–dependent mechanism controlling centromere propagation

(2008) Sylvia Erhardt et al.   JOURNAL OF CELL BIOLOGY

The RanGTP gradient - a GPS for the mitotic spindle

(2008) P. Kalab et al.   JOURNAL OF CELL SCIENCE

Modulation of the Mitotic Regulatory Network by APC-Dependent Destruction of the Cdh1 Inhibitor Acm1

(2008) Maria Enquist-Newman et al.   MOLECULAR CELL

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

(2008) Jakob Nilsson et al.   NATURE CELL BIOLOGY

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

(2008) Helfrid Hochegger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY