Genomic variation in the MAP3K5 gene is associated with β-thalassemia disease severity and hydroxyurea treatment efficacy

Hydroxycarbamide alters erythroid gene expression in children with sickle cell anaemia

(2012) Jonathan M. Flanagan et al.   BRITISH JOURNAL OF HAEMATOLOGY

A Single Nucleotide Polymorphism in theHBBP1Gene in the Human β-Globin Locus is Associated with a Mild β-Thalassemia Disease Phenotype

(2012) Emily Giannopoulou et al.   HEMOGLOBIN

6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner

(2012) Nikola Kotur et al.   PHARMACOGENOMICS

KLF10gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients

(2012) Joseph Borg et al.   PHARMACOGENOMICS

Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia

(2011) R. E. Ware et al.   BLOOD

A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

(2011) J. J. Farrell et al.   BLOOD

Transcriptional regulation and pharmacogenomics

(2011) Marianthi Georgitsi et al.   PHARMACOGENOMICS

Region-Specific Genetic Heterogeneity ofHBBMutation Distribution in South-Western Greece

(2010) Adamantia Papachatzopoulou et al.   HEMOGLOBIN

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

(2010) Joseph Borg et al.   NATURE GENETICS

Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation

(2010) Geneviève Galarneau et al.   NATURE GENETICS

Functional analysis of the role of theTPMTgene promoter VNTR polymorphism inTPMTgene transcription

(2010) Branka Zukic et al.   PHARMACOGENOMICS

The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells

(2009) K. Wahlberg et al.   BLOOD

The roles of ASK family proteins in stress responses and diseases

(2009) Kazuki Hattori et al.   Cell Communication and Signaling

SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies

(2009) Zongli Xu et al.   NUCLEIC ACIDS RESEARCH

Genetic Variation on Chromosome 6 Influences F Cell Levels in Healthy Individuals of African Descent and HbF Levels in Sickle Cell Patients

(2009) Lisa E. Creary et al.   PLoS One

Pharmacogenomics and Therapeutics of Hemoglobinopathies

(2008) George P. Patrinos et al.   HEMOGLOBIN

Hydroxyurea for the Treatment of Sickle Cell Anemia

(2008) Orah S. Platt   NEW ENGLAND JOURNAL OF MEDICINE

DNA polymorphisms at the BCL11A, HBS1L-MYB, and  -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

(2008) G. Lettre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA