Approach for chemosensitization of cisplatin-resistant ovarian cancer by cucurbitacin B

Silencing of the STAT3 signaling pathway reverses the inherent and induced chemoresistance of human ovarian cancer cells

(2013) Zhiqiang Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular aspects of cancer cell resistance to chemotherapy

(2013) Magali Rebucci et al.   BIOCHEMICAL PHARMACOLOGY

Cucurbitacin B potently suppresses non-small-cell lung cancer growth: Identification of intracellular thiols as critical targets

(2013) Hina Kausar et al.   CANCER LETTERS

Cisplatin Resistance Associated with PARP Hyperactivation

(2013) J. Michels et al.   CANCER RESEARCH

Biological activities and potential molecular targets of cucurbitacins

(2012) Xiuping Chen et al.   ANTI-CANCER DRUGS

Glutathione levels in human tumors

(2012) Michael P. Gamcsik et al.   BIOMARKERS

Reactive Oxygen Species in Health and Disease

(2012) Assim A. Alfadda et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest

(2012) Suwit Duangmano et al.   Journal of Oncology

Molecular approaches to personalizing management of ovarian cancer

(2011) R. C. Bast   ANNALS OF ONCOLOGY

In vitro and QSAR studies of cucurbitacins on HepG2 and HSC-T6 liver cell lines

(2011) Judit Bartalis et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma

(2011) Dhong Hyun Lee et al.   CANCER LETTERS

Expression of Poly (Adenosine Diphosphate-Ribose) Polymerase and p53 in Epithelial Ovarian Cancer and Their Role in Prognosis and Disease Outcome

(2011) Heidi Godoy et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Cucurbitacin B suppresses the transactivation activity of RelA/p65

(2011) Hong Ri Jin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ovarian Cancer Spheroids Use Myosin-Generated Force to Clear the Mesothelium

(2011) Marcin P. Iwanicki et al.   Cancer Discovery

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

(2010) Gabriela B Iwanski et al.   BRITISH JOURNAL OF PHARMACOLOGY

Trichostatin A restores Apaf-1 function in chemoresistant ovarian cancer cells

(2010) Lijun Tan et al.   CANCER

Nuclear factor κB transcription factors are coexpressed and convey a poor outcome in ovarian cancer

(2010) Christina M. Annunziata et al.   CANCER

Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration

(2010) Kin Tak Chan et al.   CANCER LETTERS

Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin

(2010) Tingyan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear cyclin B1 is overexpressed in low-malignant-potential ovarian tumors but not in epithelial ovarian cancer

(2009) Hong Zheng et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562

(2009) Kin Tak Chan et al.   CANCER LETTERS

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols