Peripherally Cross-Linking the Shell of Core-Shell Polymer Micelles Decreases Premature Release of Physically Loaded Combretastatin A4 in Whole Blood and Increases its Mean Residence Time and Subsequent Potency Against Primary Murine Breast Tumors After IV Administration

标题
Peripherally Cross-Linking the Shell of Core-Shell Polymer Micelles Decreases Premature Release of Physically Loaded Combretastatin A4 in Whole Blood and Increases its Mean Residence Time and Subsequent Potency Against Primary Murine Breast Tumors After IV Administration
作者
关键词
drug delivery, peripheral shell cross-linking, pluronic F127, poloxamer 407, polymer nanocarriers, premature drug release, vascular disrupting agents
出版物
PHARMACEUTICAL RESEARCH
Volume 32, Issue 3, Pages 1028-1044
出版商
Springer Nature
发表日期
2014-09-16
DOI
10.1007/s11095-014-1515-z

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