Pharmaceutical properties of calycosin, the major bioactive isoflavonoid in the dry root extract ofRadix astragali

Calycosin Induces Apoptosis by Upregulation of RASD1 in Human Breast Cancer Cells MCF-7

(2013) J. Tian et al.   HORMONE AND METABOLIC RESEARCH

On-line surface plasmon resonance-high performance liquid chromatography–tandem mass spectrometry for analysis of human serum albumin binders from Radix Astragali

(2013) Yuping Zhang et al.   JOURNAL OF CHROMATOGRAPHY A

Clinical and Experimental Effectiveness of Astragali Compound in the Treatment of Chronic Viral Hepatitis B

(2013) LL Tang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Targeting the B-Cell Lymphoma/Leukemia 2 Family in Cancer

(2012) Matthew S. Davids et al.   JOURNAL OF CLINICAL ONCOLOGY

Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats

(2012) Chao Guo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Study of the Effects of Total Flavonoids of Astragalus on Atherosclerosis Formation and Potential Mechanisms

(2012) Deqing Wang et al.   Oxidative Medicine and Cellular Longevity

Stobadine attenuates impairment of an intestinal barrier model caused by 4-hydroxynonenal

(2012) Marina Cindric et al.   TOXICOLOGY IN VITRO

Preparation and antioxidant activity of Radix Astragali residues extracts rich in calycosin and formononetin

(2011) Cai-Yun Chen et al.   BIOCHEMICAL ENGINEERING JOURNAL

Protective Effect of Soy Isoflavone Genistein on Ischemia-Reperfusion in the Rat Small Intestine

(2011) Yuki Sato et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Calycosin promotes proliferation of estrogen receptor-positive cells via estrogen receptors and ERK1/2 activation in vitro and in vivo

(2011) Jian Chen et al.   CANCER LETTERS

Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity

(2011) Bao-Shan Zhao et al.   Innovative Food Science & Emerging Technologies

Calycosin protects HUVECs from advanced glycation end products-induced macrophage infiltration

(2011) Youhua Xu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Calycosin Stimulates Proliferation of Estrogen Receptor-Positive Human Breast Cancer Cells Through Downregulation of Bax Gene Expression and Upregulation of Bcl-2 Gene Expression at Low Concentrations

(2011) Jian Chen et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Transcriptional profiling of angiogenesis activities of calycosin in zebrafish

(2011) Shang Li et al.   Molecular BioSystems

Metabolism of calycosin, an isoflavone from Astragali Radix, in zebrafish larvae

(2011) Guang Hu et al.   XENOBIOTICA

Genistein Aglycone: A Dual Mode of Action Anti-Osteoporotic Soy Isoflavone Rebalancing Bone Turnover Towards Bone Formation

(2010) A. Bitto et al.   CURRENT MEDICINAL CHEMISTRY

Phytoestrogen bavachin mediates anti-inflammation targeting IκB kinase-IκBα-NF-κB signaling pathway in chondrocytes in vitro

(2010) Cheng-Chung Cheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of flavonoids from Astragalus complanatus on radiation induced damages in mice

(2010) Lin Qi et al.   FITOTERAPIA

The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity

(2010) Ruby LC Hoo et al.   Nutrition & Metabolism

Calycosin Promotes Angiogenesis Involving Estrogen Receptor and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Zebrafish and HUVEC

(2010) Jing Yan Tang et al.   PLoS One

Apoptosis in cancer: Key molecular signaling pathways and therapy targets

(2009) Claudia Burz et al.   ACTA ONCOLOGICA

Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway

(2009) S. Jin et al.   ANNALS OF ONCOLOGY

Protection of PC12 Cells against Superoxide-induced Damage by Isoflavonoids from Astragalus mongholicus

(2009) De-Hong YU et al.   BIOMEDICAL AND ENVIRONMENTAL SCIENCES

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

(2009) M. H. Kang et al.   CLINICAL CANCER RESEARCH

RAGE signaling in inflammation and arterial aging

(2009) Li Lin   Frontiers in Bioscience-Landmark

Isolation and purification of flavonoid glucosides from Radix Astragali by high-speed counter-current chromatography

(2009) Weihua Xiao et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Systematic review of the renal protective effect of Astragalus membranaceus (root) on diabetic nephropathy in animal models

(2009) Juqian Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Pathologic Continuum of Diabetic Vascular Disease

(2009) Gabriela Orasanu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Qualitative and quantitative analysis of Radix Astragali products by fast high-performance liquid chromatography-diode array detection coupled with time-of-flight mass spectrometry through dynamic adjustment of fragmentor voltage

(2008) Lian-Wen Qi et al.   JOURNAL OF CHROMATOGRAPHY A

Daidzein administration in vivo reduces myocardial injury in a rat ischemia/reperfusion model by inhibiting NF-kB activation

(2008) Jong Woo Kim et al.   LIFE SCIENCES

Neuroprotective effects of berberine on stroke models in vitro and in vivo

(2008) Xi-Qiao Zhou et al.   NEUROSCIENCE LETTERS

Protective effect of isoflavones from Trifolium pratense on dopaminergic neurons

(2008) Han-Qing Chen et al.   NEUROSCIENCE RESEARCH

Antihyperglycemic and antioxidative effects of a herbal formulation ofRadix Astragali,Radix CodonopsisandCortex Lyciiin a mouse model of type 2 diabetes mellitus

(2008) Judy Yuet-Wa Chan et al.   PHYTOTHERAPY RESEARCH

Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk

(2007) Minsook Ryu et al.   JOURNAL OF ETHNOPHARMACOLOGY