Canavan disease: Clinical features and recent advances in research

Dietary triheptanoin rescues oligodendrocyte loss, dysmyelination and motor function in the nur7 mouse model of Canavan disease

(2013) Jeremy S. Francis et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Astroglial Redistribution of Aquaporin 4 During Spongy Degeneration in a Canavan Disease Mouse Model

(2013) Tim Clarner et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Gene Therapy for Canavan's Disease Takes a Step Forward

(2013) Seemin S Ahmed et al.   MOLECULAR THERAPY

Aspartoacylase Supports Oxidative Energy Metabolism during Myelination

(2012) Jeremy S Francis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Long-Term Follow-Up After Gene Therapy for Canavan Disease

(2012) P. Leone et al.   Science Translational Medicine

A safety trial of high dose glyceryl triacetate for Canavan disease

(2011) Reeval Segel et al.   MOLECULAR GENETICS AND METABOLISM

Lithium citrate reduces excessive intra-cerebral N-acetyl aspartate in Canavan disease

(2010) Mitra Assadi et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease

(2010) Peethambaran Arun et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Pyruvate carboxylase deficiency: Mechanisms, mimics and anaplerosis

(2010) Isaac Marin-Valencia et al.   MOLECULAR GENETICS AND METABOLISM

Aspartoacylase deficiency affects early postnatal development of oligodendrocytes and myelination

(2010) Natalia S. Mattan et al.   NEUROBIOLOGY OF DISEASE

Epigenetic regulation of oligodendrocyte identity

(2010) Jia Liu et al.   TRENDS IN NEUROSCIENCES

The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes

(2009) K. Kolodziejczyk et al.   BRAIN

Lack of aspartoacylase activity disrupts survival and differentiation of neural progenitors and oligodendrocytes in a mouse model of Canavan disease

(2009) Shalini Kumar et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Intracerebroventricular administration of N-acetylaspartic acid impairs antioxidant defenses and promotes protein oxidation in cerebral cortex of rats

(2009) Carolina Didonet Pederzolli et al.   METABOLIC BRAIN DISEASE

Myelin Lipid Abnormalities in the Aspartoacylase-Deficient Tremor Rat

(2008) Jianfeng Wang et al.   NEUROCHEMICAL RESEARCH

Developmental and regional distribution of aspartoacylase in rat brain tissue

(2003) Kishore K. Bhakoo et al.   JOURNAL OF NEUROCHEMISTRY