Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

Does bafilomycin A1block the fusion of autophagosomes with lysosomes?

(2014) Daniel J. Klionsky et al.   Autophagy

A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking

(2014) Prisca Liberali et al.   CELL

Principles of membrane tethering and fusion in endosome and lysosome biogenesis

(2014) Daniel Kümmel et al.   CURRENT OPINION IN CELL BIOLOGY

SNARE-ing the structures of Sec1/Munc18 proteins

(2014) Julia K Archbold et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Dynamic Interface between Vacuoles and Mitochondria in Yeast

(2014) Yael Elbaz-Alon et al.   DEVELOPMENTAL CELL

Cellular Metabolism Regulates Contact Sites between Vacuoles and Mitochondria

(2014) Carina Hönscher et al.   DEVELOPMENTAL CELL

Loss of the Sec1/Munc18-family proteins VPS-33.2 and VPS-33.1 bypasses a block in endosome maturation in Caenorhabditis elegans

(2014) Jachen A. Solinger et al.   MOLECULAR BIOLOGY OF THE CELL

Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1

(2014) Jared L. Delahaye et al.   MOLECULAR BIOLOGY OF THE CELL

The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

(2014) Peidu Jiang et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila

(2014) Szabolcs Takáts et al.   MOLECULAR BIOLOGY OF THE CELL

Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein–protein interactions

(2014) Georg H. H. Borner et al.   MOLECULAR BIOLOGY OF THE CELL

Mammalian CORVET Is Required for Fusion and Conversion of Distinct Early Endosome Subpopulations

(2014) Enrico D. Perini et al.   TRAFFIC

The Biogenesis of Lysosomes and Lysosome-Related Organelles

(2014) J. P. Luzio et al.   Cold Spring Harbor Perspectives in Biology

A distinct tethering step is vital for vacuole membrane fusion

(2014) Michael Zick et al.   eLife

SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18

(2014) Braden T Lobingier et al.   eLife

Lysosome-related organelles: unusual compartments become mainstream

(2013) Michael S Marks et al.   CURRENT OPINION IN CELL BIOLOGY

Self-Assembly of VPS41 Promotes Sorting Required for Biogenesis of the Regulated Secretory Pathway

(2013) Cédric S. Asensio et al.   DEVELOPMENTAL CELL

Tethering complexes in the endocytic pathway: CORVET and HOPS

(2013) Jachen A. Solinger et al.   FEBS Journal

Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes

(2013) K. Tornieri et al.   HUMAN MOLECULAR GENETICS

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans

(2013) Ayaka Sasaki et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*

(2013) Richard W. Baker et al.   PLoS One

Comparative Genomic Analysis of Multi-Subunit Tethering Complexes Demonstrates an Ancient Pan-Eukaryotic Complement and Sculpting in Apicomplexa

(2013) Christen M. Klinger et al.   PLoS One

The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes

(2013) H. J. k. Balderhaar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

(2013) S. C. Graham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy

(2013) Han-Ming Shen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tethering the assembly of SNARE complexes

(2013) WanJin Hong et al.   TRENDS IN CELL BIOLOGY

hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins

(2013) Maaike S. Pols et al.   Nature Communications

The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet  -granule biogenesis

(2012) D. Urban et al.   BLOOD

Impaired Stimulation of p38α-MAPK/Vps41-HOPS by LPS from Pathogenic Coxiella burnetii Prevents Trafficking to Microbicidal Phagolysosomes

(2012) Abdoulaye Oury Barry et al.   Cell Host & Microbe

Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex

(2012) Braden T. Lobingier et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

(2012) David A. Tumbarello et al.   NATURE CELL BIOLOGY

Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex

(2012) C. Brocker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HOPS Proteins hVps41 and hVps39 Are Required for Homotypic and Heterotypic Late Endosome Fusion

(2012) Maaike S. Pols et al.   TRAFFIC

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

(2011) Salil Garg et al.   IMMUNITY

Thefull-of-bacteriagene is required for phagosome maturation during immune defense inDrosophila

(2011) Mohammed Ali Akbar et al.   JOURNAL OF CELL BIOLOGY

Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic

(2011) Rachael L. Plemel et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

(2011) Ian G. Ganley et al.   MOLECULAR CELL

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Targeting protein-trafficking pathways alters melanoma treatment sensitivity

(2011) Z.-m. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization

(2010) Andrew R Cullinane et al.   NATURE GENETICS

The SM protein Vps33 and the t-SNARE Habc domain promote fusion pore opening

(2010) Michel Pieren et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Vps-C complexes: gatekeepers of endolysosomal traffic

(2009) Daniel P Nickerson et al.   CURRENT OPINION IN CELL BIOLOGY

Coiled-coil interactions are required for post-Golgi R-SNARE trafficking

(2009) David E Gordon et al.   EMBO REPORTS

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

(2009) M. N. J. Seaman et al.   JOURNAL OF CELL SCIENCE

The SM Protein Car/Vps33A Regulates SNARE-mediated Trafficking to Lysosomes and Lysosome-related Organelles

(2009) Mohammed A. Akbar et al.   MOLECULAR BIOLOGY OF THE CELL

The Vam6 GEF Controls TORC1 by Activating the EGO Complex

(2009) Matteo Binda et al.   MOLECULAR CELL

SPE-39 Family Proteins Interact with the HOPS Complex and Function in Lysosomal Delivery

(2008) Guang-dan Zhu et al.   MOLECULAR BIOLOGY OF THE CELL

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY