Role of p53 in the Progression from Ochratoxin A-Induced DNA Damage to Gene Mutations in the Kidneys of Mice

Recent developments in the use of γ -H2AX as a quantitative DNA double-strand break biomarker

(2016) Christophe E. Redon et al.   Aging-US

Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes

(2014) Swetha Inturi et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Downregulation of Rad51 participates in OTA-induced DNA double-strand breaks in GES-1 cells in vitro

(2014) Hongguang Lian et al.   TOXICOLOGY LETTERS

Mutant frequency in comparison to oxidative DNA damage induced by ochratoxin A in L5178Ytk+/−(3.7.2C) mouse lymphoma cells

(2013) Rahat Ali et al.   DRUG AND CHEMICAL TOXICOLOGY

Molecular mechanisms underlying ochratoxin A-induced genotoxicity: global gene expression analysis suggests induction of DNA double-strand breaks and cell cycle progression

(2013) Daisuke Hibi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats

(2013) Ken Kuroda et al.   MUTAGENESIS

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

Effects of p53 knockout on ochratoxin A-induced genotoxicity in p53-deficient gpt delta mice

(2012) Daisuke Hibi et al.   TOXICOLOGY

Mutagenicity of Ochratoxin A and Its Hydroquinone Metabolite in the SupF Gene of the Mutation Reporter Plasmid Ps189

(2012) Steven A. Akman et al.   Toxins

Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles

(2011) Steve Quiros et al.   CELL CYCLE

An Update on Direct Genotoxicity as a Molecular Mechanism of Ochratoxin A Carcinogenicity

(2011) Annie Pfohl-Leszkowicz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Site-Specific In Vivo Mutagenicity in the Kidney of gpt Delta Rats Given a Carcinogenic Dose of Ochratoxin A

(2011) Daisuke Hibi et al.   TOXICOLOGICAL SCIENCES

Break-Induced Replication Is Highly Inaccurate

(2011) Angela Deem et al.   PLOS BIOLOGY

Break-induced replication: What is it and what is it for?

(2010) Bertrand Llorente et al.   CELL CYCLE

Antigenotoxic effects of p53 on spontaneous and ultraviolet light B-induced deletions in the epidermis of gpt delta transgenic mice

(2010) Kenichi Masumura et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity

(2009) Melanie Adler et al.   CARCINOGENESIS

BH3-only proteins in apoptosis and beyond: an overview

(2009) E Lomonosova et al.   ONCOGENE